Mercury in PDB 12ca: Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121

Enzymatic activity of Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121

All present enzymatic activity of Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121:
4.2.1.1;

Protein crystallography data

The structure of Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121, PDB code: 12ca was solved by S.K.Nair, D.W.Christianson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	N/A / 2.40
*Space group*	P 1 2₁ 1
*Cell size a, b, c (Å), α, β, γ (°)*	42.700, 41.700, 73.000, 90.00, 104.60, 90.00
*R / R_free (%)*	n/a / n/a

Other elements in 12ca:

The structure of Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121 also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

Mercury Binding Sites:

The binding sites of Mercury atom in the Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121 (pdb code 12ca). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total only one binding site of Mercury was determined in the Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121, PDB code: 12ca:

Mercury binding site 1 out of 1 in 12ca

Go back to

Mercury Binding Sites List in 12ca

Mercury binding site 1 out of 1 in the Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121

Mono view

Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121 within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Hg263 b:15.9 occ:1.00	SG	A:CYS206	2.3	8.7	1.0
	O	A:GLN137	3.0	13.4	1.0
	CB	A:CYS206	3.1	8.4	1.0
	O	A:GLU205	3.4	7.9	1.0
	C	A:GLN137	3.5	13.6	1.0
	CA	A:CYS206	3.6	8.4	1.0
	C	A:GLU205	3.7	8.2	1.0
	N	A:GLN137	3.7	14.4	1.0
	O	A:VAL135	3.7	15.7	1.0
	N	A:CYS206	3.7	8.2	1.0
	O	A:HOH297	3.9	2.4	1.0
	O	A:HOH315	4.0	9.4	1.0
	C	A:VAL135	4.0	15.4	1.0
	C	A:GLN136	4.1	14.9	1.0
	N	A:PRO138	4.1	13.1	1.0
	CA	A:GLN137	4.1	14.0	1.0
	CA	A:GLN136	4.4	15.2	1.0
	N	A:GLN136	4.4	15.3	1.0
	CA	A:PRO138	4.4	12.8	1.0
	N	A:GLU205	4.5	8.3	1.0
	O	A:GLN136	4.6	14.9	1.0
	CA	A:GLU205	4.7	8.2	1.0
	CA	A:VAL135	4.9	15.4	1.0
	CB	A:LEU204	4.9	8.8	1.0
	O	A:ALA134	4.9	15.6	1.0
	C	A:LEU204	4.9	8.6	1.0
	C	A:CYS206	5.0	8.3	1.0

Reference:

S.K.Nair, T.L.Calderone, D.W.Christianson, C.A.Fierke. Altering the Mouth of A Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121. J.Biol.Chem. V. 266 17320 1991.
ISSN: ISSN 0021-9258
PubMed: 1910042

Page generated: Sat Aug 10 23:17:34 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy