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Mercury in PDB 1cin: The Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors

Enzymatic activity of The Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors

All present enzymatic activity of The Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors:
4.2.1.1;

Protein crystallography data

The structure of The Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors, PDB code: 1cin was solved by G.M.Smith, R.S.Alexander, D.W.Christianson, B.M.Mckeever, G.S.Ponticello, J.P.Springer, W.C.Randall, J.J.Baldwin, C.N.Habecker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 2.10
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.830, 42.040, 72.620, 90.00, 104.78, 90.00
R / Rfree (%) n/a / n/a

Other elements in 1cin:

The structure of The Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Mercury Binding Sites:

The binding sites of Mercury atom in the The Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors (pdb code 1cin). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total only one binding site of Mercury was determined in the The Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors, PDB code: 1cin:

Mercury binding site 1 out of 1 in 1cin

Go back to Mercury Binding Sites List in 1cin
Mercury binding site 1 out of 1 in the The Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of The Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg263

b:16.1
occ:1.00
 HG A:MMC263 0.0 16.1 1.0
C A:MMC263 2.0 13.6 1.0
SG A:CYS206 2.2 9.1 1.0
O A:GLN137 3.1 13.9 1.0
CB A:CYS206 3.1 9.7 1.0
O A:GLU205 3.2 8.2 1.0
CA A:CYS206 3.5 9.5 1.0
C A:GLN137 3.5 14.7 1.0
O A:VAL135 3.5 12.5 1.0
C A:GLU205 3.6 8.7 1.0
N A:CYS206 3.7 9.1 1.0
N A:GLN137 3.8 15.7 1.0
C A:GLN136 4.0 15.2 1.0
N A:PRO138 4.0 14.3 1.0
O A:HOH365 4.0 17.8 1.0
C A:VAL135 4.1 13.0 1.0
CA A:GLN137 4.2 15.4 1.0
CA A:PRO138 4.3 12.8 1.0
O A:HOH397 4.3 12.1 1.0
O A:GLN136 4.4 15.7 1.0
CA A:GLN136 4.4 14.6 1.0
N A:GLU205 4.5 8.7 1.0
N A:GLN136 4.6 13.1 1.0
CA A:GLU205 4.6 8.3 1.0
CB A:LEU204 4.8 8.1 1.0
C A:CYS206 4.9 8.8 1.0
CA A:VAL135 5.0 12.1 1.0

Reference:

G.M.Smith, R.S.Alexander, D.W.Christianson, B.M.Mckeever, G.S.Ponticello, J.P.Springer, W.C.Randall, J.J.Baldwin, C.N.Habecker. Positions of His-64 and A Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors. Protein Sci. V. 3 118 1994.
ISSN: ISSN 0961-8368
PubMed: 8142888
Page generated: Sat Aug 10 23:23:29 2024

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