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Mercury in PDB 1cra: The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole

Enzymatic activity of The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole

All present enzymatic activity of The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole:
4.2.1.1;

Protein crystallography data

The structure of The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole, PDB code: 1cra was solved by S.Mangani, A.Liljas, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 1.90
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.700, 41.700, 73.000, 90.00, 104.60, 90.00
R / Rfree (%) n/a / n/a

Other elements in 1cra:

The structure of The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Mercury Binding Sites:

The binding sites of Mercury atom in the The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole (pdb code 1cra). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total only one binding site of Mercury was determined in the The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole, PDB code: 1cra:

Mercury binding site 1 out of 1 in 1cra

Go back to Mercury Binding Sites List in 1cra
Mercury binding site 1 out of 1 in the The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg495

b:10.6
occ:0.14
O A:HOH362 2.0 22.1 1.0
O A:HOH448 2.4 32.4 1.0
CB A:CYS206 2.9 11.9 1.0
O A:VAL135 3.0 14.5 1.0
O A:GLN137 3.2 10.5 1.0
O A:GLU205 3.4 7.8 1.0
CA A:CYS206 3.4 4.8 1.0
N A:GLN137 3.4 8.1 1.0
C A:GLN137 3.5 12.2 1.0
C A:GLU205 3.5 10.9 1.0
C A:GLN136 3.6 22.8 1.0
N A:CYS206 3.6 5.0 1.0
O A:HOH331 3.7 12.1 1.0
C A:VAL135 3.9 21.9 1.0
O A:HOH365 3.9 29.8 1.0
CA A:GLN137 4.0 5.2 1.0
O A:GLN136 4.0 19.7 1.0
CA A:GLN136 4.1 12.4 1.0
N A:PRO138 4.1 13.5 1.0
N A:GLU205 4.1 7.5 1.0
SG A:CYS206 4.3 13.1 1.0
CA A:PRO138 4.4 7.7 1.0
CA A:GLU205 4.4 7.0 1.0
N A:GLN136 4.4 8.0 1.0
CB A:LEU204 4.5 8.3 1.0
O A:HOH483 4.6 39.4 1.0
C A:LEU204 4.7 4.7 1.0
C A:CYS206 4.9 4.5 1.0
CD A:PRO138 5.0 18.4 1.0

Reference:

S.Mangani, A.Liljas. Crystal Structure of the Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-Triazole. J.Mol.Biol. V. 232 9 1993.
ISSN: ISSN 0022-2836
PubMed: 8331673
DOI: 10.1006/JMBI.1993.1365
Page generated: Sun Dec 13 19:02:15 2020

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