Atomistry » Mercury » PDB 1czs-1g4o » 1dr4
Atomistry »
  Mercury »
    PDB 1czs-1g4o »
      1dr4 »

Mercury in PDB 1dr4: Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes

Enzymatic activity of Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes

All present enzymatic activity of Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes:
1.5.1.3;

Protein crystallography data

The structure of Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes, PDB code: 1dr4 was solved by M.A.Mctigue, J.F.Davies /Ii, B.T.Kaufman, N.-H.Xuong, J.Kraut, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 2.40
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 89.080, 48.290, 64.320, 90.00, 124.80, 90.00
R / Rfree (%) n/a / n/a

Other elements in 1dr4:

The structure of Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes also contains other interesting chemical elements:

Calcium (Ca) 1 atom

Mercury Binding Sites:

The binding sites of Mercury atom in the Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes (pdb code 1dr4). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 2 binding sites of Mercury where determined in the Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes, PDB code: 1dr4:
Jump to Mercury binding site number: 1; 2;

Mercury binding site 1 out of 2 in 1dr4

Go back to Mercury Binding Sites List in 1dr4
Mercury binding site 1 out of 2 in the Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg190

b:54.5
occ:0.75
HG A:HG190 0.0 54.5 0.8
HG A:HG190 2.3 60.2 0.2
SG A:CYS11 2.4 43.9 0.8
CB A:CYS11 2.9 50.0 0.2
O A:PHE142 2.9 45.5 1.0
OD1 A:ASN13 2.9 56.4 1.0
O A:HOH705 2.9 77.9 1.0
ND2 A:ASN13 3.0 61.6 1.0
N A:PHE142 3.1 42.3 1.0
SG A:CYS11 3.1 52.4 0.2
CG A:ASN13 3.2 52.9 1.0
CB A:CYS11 3.3 37.1 0.8
CA A:GLU141 3.7 48.7 1.0
N A:ASN13 3.7 29.9 1.0
OG A:SER144 3.7 31.0 1.0
N A:GLN12 3.8 36.8 1.0
C A:PHE142 3.8 41.9 1.0
C A:GLU141 3.9 49.3 1.0
CA A:CYS11 4.0 31.0 1.0
C A:CYS11 4.0 34.0 1.0
CA A:PHE142 4.0 38.8 1.0
O A:HIS140 4.2 40.9 1.0
CB A:GLU141 4.4 53.0 1.0
CB A:ASN13 4.4 46.2 1.0
N A:GLY15 4.5 22.4 1.0
CA A:GLN12 4.5 38.5 1.0
CA A:ASN13 4.6 37.1 1.0
C A:GLN12 4.6 36.0 1.0
CB A:PHE142 4.7 34.0 1.0
N A:CYS11 4.8 28.2 1.0
O A:CYS11 4.8 35.1 1.0
N A:GLU141 4.8 44.6 1.0
CA A:GLY15 4.8 20.4 1.0
CB A:SER144 4.9 25.6 1.0
C A:HIS140 4.9 44.0 1.0
CD1 A:PHE142 4.9 35.0 1.0
CG A:GLU141 5.0 67.3 1.0

Mercury binding site 2 out of 2 in 1dr4

Go back to Mercury Binding Sites List in 1dr4
Mercury binding site 2 out of 2 in the Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg190

b:60.2
occ:0.25
HG A:HG190 0.0 60.2 0.2
SG A:CYS11 1.5 43.9 0.8
HG A:HG190 2.3 54.5 0.8
SG A:CYS11 2.5 52.4 0.2
OG A:SER144 2.5 31.0 1.0
CB A:CYS11 3.2 37.1 0.8
O A:PHE142 3.3 45.5 1.0
CB A:CYS11 3.3 50.0 0.2
O A:HOH705 3.3 77.9 1.0
O A:GLY15 3.5 22.2 1.0
CA A:GLY15 3.6 20.4 1.0
CB A:SER144 3.7 25.6 1.0
C A:GLY15 3.8 22.3 1.0
CG A:PRO23 3.8 28.6 1.0
CA A:CYS11 3.9 31.0 1.0
N A:GLY15 3.9 22.4 1.0
ND2 A:ASN13 3.9 61.6 1.0
CZ3 A:TRP24 4.0 24.1 1.0
CB A:PRO23 4.0 25.4 1.0
N A:CYS11 4.0 28.2 1.0
N A:PHE142 4.2 42.3 1.0
C A:PHE142 4.2 41.9 1.0
CB A:PHE142 4.5 34.0 1.0
CA A:PHE142 4.5 38.8 1.0
C A:CYS11 4.5 34.0 1.0
CE3 A:TRP24 4.6 30.9 1.0
CG A:ASN13 4.7 52.9 1.0
N A:ILE16 4.7 21.3 1.0
OD1 A:ASN13 4.8 56.4 1.0
CD1 A:PHE142 4.8 35.0 1.0
CA A:SER144 4.9 30.6 1.0
N A:GLN12 4.9 36.8 1.0
N A:SER144 4.9 28.7 1.0
CH2 A:TRP24 5.0 29.1 1.0

Reference:

M.A.Mctigue, J.F.Davies Ii, B.T.Kaufman, N.-H.Xuong, J.Kraut. Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes To Be Published.
Page generated: Wed Oct 28 18:39:07 2020

Last articles

Xe in 6AYK
Xe in 6QII
Xe in 6ASM
Xe in 5NSW
Xe in 6FY9
Xe in 5O1K
Xe in 5O27
Xe in 5M69
Xe in 5KPU
Xe in 5I63
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy