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Atomistry » Mercury » PDB 1g52-1irk » 1i91 » |
Mercury in PDB 1i91: Carbonic Anhydrase II Complexed with Al-6619 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1- DioxideEnzymatic activity of Carbonic Anhydrase II Complexed with Al-6619 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide
All present enzymatic activity of Carbonic Anhydrase II Complexed with Al-6619 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase II Complexed with Al-6619 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide, PDB code: 1i91
was solved by
C.-Y.Kim,
J.S.Chang,
J.Liao,
J.A.May,
D.W.Christianson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1i91:
The structure of Carbonic Anhydrase II Complexed with Al-6619 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide also contains other interesting chemical elements:
Mercury Binding Sites:
The binding sites of Mercury atom in the Carbonic Anhydrase II Complexed with Al-6619 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide
(pdb code 1i91). This binding sites where shown within
5.0 Angstroms radius around Mercury atom.
In total only one binding site of Mercury was determined in the Carbonic Anhydrase II Complexed with Al-6619 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide, PDB code: 1i91: Mercury binding site 1 out of 1 in 1i91Go back to![]() ![]()
Mercury binding site 1 out
of 1 in the Carbonic Anhydrase II Complexed with Al-6619 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide
![]() Mono view ![]() Stereo pair view
Reference:
C.Y.Kim,
D.A.Whittington,
J.S.Chang,
J.Liao,
J.A.May,
D.W.Christianson.
Structural Aspects of Isozyme Selectivity in the Binding of Inhibitors to Carbonic Anhydrases II and IV. J.Med.Chem. V. 45 888 2002.
Page generated: Sat Aug 10 23:59:15 2024
ISSN: ISSN 0022-2623 PubMed: 11831900 DOI: 10.1021/JM010163D |
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