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Atomistry » Mercury » PDB 1is9-1obh » 1k4t » |
Mercury in PDB 1k4t: Human Dna Topoisomerase I (70 kDa) in Complex with the Poison Topotecan and Covalent Complex with A 22 Base Pair Dna DuplexEnzymatic activity of Human Dna Topoisomerase I (70 kDa) in Complex with the Poison Topotecan and Covalent Complex with A 22 Base Pair Dna Duplex
All present enzymatic activity of Human Dna Topoisomerase I (70 kDa) in Complex with the Poison Topotecan and Covalent Complex with A 22 Base Pair Dna Duplex:
5.99.1.2; Protein crystallography data
The structure of Human Dna Topoisomerase I (70 kDa) in Complex with the Poison Topotecan and Covalent Complex with A 22 Base Pair Dna Duplex, PDB code: 1k4t
was solved by
B.L.Staker,
K.Hjerrild,
M.D.Feese,
C.A.Behnke,
A.B.Burgin Jr.,
L.J.Stewart,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Mercury Binding Sites:
The binding sites of Mercury atom in the Human Dna Topoisomerase I (70 kDa) in Complex with the Poison Topotecan and Covalent Complex with A 22 Base Pair Dna Duplex
(pdb code 1k4t). This binding sites where shown within
5.0 Angstroms radius around Mercury atom.
In total only one binding site of Mercury was determined in the Human Dna Topoisomerase I (70 kDa) in Complex with the Poison Topotecan and Covalent Complex with A 22 Base Pair Dna Duplex, PDB code: 1k4t: Mercury binding site 1 out of 1 in 1k4tGo back to Mercury Binding Sites List in 1k4t
Mercury binding site 1 out
of 1 in the Human Dna Topoisomerase I (70 kDa) in Complex with the Poison Topotecan and Covalent Complex with A 22 Base Pair Dna Duplex
Mono view Stereo pair view
Reference:
B.L.Staker,
K.Hjerrild,
M.D.Feese,
C.A.Behnke,
A.B.Burgin Jr.,
L.J.Stewart.
The Mechanism of Topoisomerase I Poisoning By A Camptothecin Analog Proc.Natl.Acad.Sci.Usa V. 99 15387 2002.
Page generated: Sun Dec 13 19:03:33 2020
ISSN: ISSN 0027-8424 PubMed: 12426403 DOI: 10.1073/PNAS.242259599 |
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