Chemical elements
  Mercury
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    PDB 12ca-1dr4
    PDB 1dr5-1ht3
    PDB 1hzx-1mms
      1hzx
      1i8z
      1i90
      1i91
      1i9l
      1i9m
      1i9n
      1i9o
      1i9p
      1i9q
      1iac
      1if4
      1if5
      1if6
      1if7
      1if8
      1if9
      1igw
      1in0
      1irk
      1is9
      1iub
      1ixz
      1j5q
      1j99
      1jfh
      1jjv
      1joe
      1jop
      1jpr
      1jqc
      1k1e
      1k4t
      1kdg
      1kgz
      1kwp
      1kwq
      1kzl
      1l8d
      1l9a
      1l9h
      1lug
      1lz0
      1lz7
      1lzi
      1lzj
      1m3w
      1m3y
      1miu
      1mms
    PDB 1moo-1rhy
    PDB 1rnr-1zfk
    PDB 1zfq-2geh
    PDB 2gv9-2wcd
    PDB 2wiu-3k34
    PDB 3k4o-9ca2

Mercury in the structure of Human Dna Topoisomerase I (70 Kda) in Complex With the Poison Topotecan and Covalent Complex With A 22 Base Pair Dna Duplex (pdb 1k4t)






The binding sites of Mercury atom in the structure of Human Dna Topoisomerase I (70 Kda) in Complex With the Poison Topotecan and Covalent Complex With A 22 Base Pair Dna Duplex (pdb code 1k4t). This binding sites where shown with 5.0 Angstroms radius around Mercury atom.
The 1k4t structure was solved by B.L.STAKER, K.HJERRILD, M.D.FEESE, C.A.BEHNKE, A.B.BURGIN JR., L.J.STEWART, with X-Ray Crystallography technique, brief refinement statistics is given in the table below:
Resolution (A)19.9-2.1
Space groupP1211
a (A)57.093
b (A)116.260
c (A)75.217
alpha (°)90.00
beta (°)94.16
gamma (°)90.00
Rfactor (%)n/a
Rfree (%)n/a


Mercury Binding Sites:

Mercury binding site 1 out of 1 in 1k4t


Mercury binding site 1 out of 1 in 1k4t
Click to enlarge
stereopicture of Mercury binding site 1 out of 1 in 1k4t
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Mercury in the PDB 1k4t. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Mercury atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Ala486, A: Arg590, A: Asn593, A: Ala594, A: Val626, A: Leu629, A: Cys630,

conact list:


AtomAtomDistance (A)
HgCB A:Ala4863.73
HgO A:Arg5903.42
HgCB A:Arg5904.54
HgC A:Arg5904.23
HgCG A:Arg5904.89
HgCA A:Arg5904.22
HgCB A:Asn5934.49
HgC A:Asn5934.53
HgN A:Ala5943.88
HgCB A:Ala5943.75
HgCA A:Ala5944.03
HgO A:Val6264.76
HgO A:Leu6294.94
HgCB A:Leu6294.67
HgCD1 A:Leu6294.97
HgCD2 A:Leu6293.30
HgC A:Leu6294.64
HgCG A:Leu6294.48
HgN A:Cys6304.25
HgCB A:Cys6304.06
HgSG A:Cys6302.78
HgCA A:Cys6304.18

interactive model:




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