Mercury in PDB 1tlf: Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping
Protein crystallography data
The structure of Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping, PDB code: 1tlf
was solved by
A.M.Friedman,
T.O.Fischmann,
T.A.Steitz,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
N/A /
2.60
|
Space group
|
P 1 21 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
90.160,
64.730,
117.940,
90.00,
91.75,
90.00
|
R / Rfree (%)
|
22.2 /
n/a
|
Mercury Binding Sites:
The binding sites of Mercury atom in the Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping
(pdb code 1tlf). This binding sites where shown within
5.0 Angstroms radius around Mercury atom.
In total 4 binding sites of Mercury where determined in the
Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping, PDB code: 1tlf:
Jump to Mercury binding site number:
1;
2;
3;
4;
Mercury binding site 1 out
of 4 in 1tlf
Go back to
Mercury Binding Sites List in 1tlf
Mercury binding site 1 out
of 4 in the Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping
Mono view
Stereo pair view
|
A full contact list of Mercury with other atoms in the Hg binding
site number 1 of Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Hg999
b:69.2
occ:1.00
|
SG
|
A:CYS281
|
2.5
|
31.1
|
1.0
|
O
|
A:SER280
|
2.8
|
27.5
|
1.0
|
C
|
A:SER280
|
3.4
|
14.8
|
1.0
|
CA
|
A:CYS281
|
3.6
|
30.6
|
1.0
|
SD
|
B:MET223
|
3.6
|
37.2
|
1.0
|
CB
|
A:CYS281
|
3.7
|
31.1
|
1.0
|
OG
|
A:SER280
|
3.7
|
27.5
|
1.0
|
N
|
A:CYS281
|
3.8
|
30.6
|
1.0
|
CE
|
B:MET223
|
4.0
|
37.2
|
1.0
|
CD2
|
B:PHE226
|
4.1
|
26.2
|
1.0
|
CG
|
B:PHE226
|
4.1
|
26.2
|
1.0
|
NH1
|
B:ARG255
|
4.2
|
43.8
|
1.0
|
HH11
|
B:ARG255
|
4.2
|
0.0
|
1.0
|
CB
|
B:PHE226
|
4.2
|
26.2
|
1.0
|
CB
|
A:SER280
|
4.3
|
27.5
|
1.0
|
HH12
|
B:ARG255
|
4.3
|
0.0
|
1.0
|
CG
|
B:ARG255
|
4.4
|
43.8
|
1.0
|
HG
|
A:SER280
|
4.4
|
30.0
|
1.0
|
CA
|
A:SER280
|
4.5
|
14.8
|
1.0
|
CZ
|
B:ARG255
|
4.5
|
43.8
|
1.0
|
H
|
A:CYS281
|
4.6
|
0.0
|
1.0
|
CE2
|
B:PHE226
|
4.7
|
26.2
|
1.0
|
CD1
|
B:PHE226
|
4.7
|
26.2
|
1.0
|
NE
|
B:ARG255
|
4.9
|
43.8
|
1.0
|
CA
|
B:MET223
|
4.9
|
17.7
|
1.0
|
NH2
|
B:ARG255
|
4.9
|
43.8
|
1.0
|
O
|
B:ALA222
|
5.0
|
23.8
|
1.0
|
C
|
A:CYS281
|
5.0
|
30.6
|
1.0
|
|
Mercury binding site 2 out
of 4 in 1tlf
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Mercury Binding Sites List in 1tlf
Mercury binding site 2 out
of 4 in the Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping
Mono view
Stereo pair view
|
A full contact list of Mercury with other atoms in the Hg binding
site number 2 of Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Hg999
b:50.7
occ:1.00
|
CB
|
B:CYS281
|
2.2
|
33.1
|
1.0
|
SG
|
B:CYS281
|
2.6
|
33.1
|
1.0
|
SD
|
A:MET223
|
3.2
|
23.7
|
1.0
|
CA
|
B:CYS281
|
3.3
|
26.7
|
1.0
|
OG
|
B:SER280
|
3.3
|
27.8
|
1.0
|
O
|
B:SER280
|
3.4
|
27.8
|
1.0
|
HH11
|
A:ARG255
|
3.4
|
0.0
|
1.0
|
N
|
B:CYS281
|
3.4
|
26.7
|
1.0
|
C
|
B:SER280
|
3.5
|
14.3
|
1.0
|
HG
|
B:SER280
|
3.7
|
30.0
|
1.0
|
CE
|
A:MET223
|
3.9
|
23.7
|
1.0
|
H
|
B:CYS281
|
4.0
|
0.0
|
1.0
|
NH1
|
A:ARG255
|
4.0
|
34.4
|
1.0
|
HH12
|
A:ARG255
|
4.1
|
0.0
|
1.0
|
CG
|
A:PHE226
|
4.2
|
15.3
|
1.0
|
CD2
|
A:PHE226
|
4.2
|
15.3
|
1.0
|
CB
|
B:SER280
|
4.2
|
27.8
|
1.0
|
CG
|
A:ARG255
|
4.3
|
34.4
|
1.0
|
CB
|
A:PHE226
|
4.3
|
15.3
|
1.0
|
CA
|
B:SER280
|
4.5
|
14.3
|
1.0
|
C
|
B:CYS281
|
4.6
|
26.7
|
1.0
|
CD1
|
A:PHE226
|
4.6
|
15.3
|
1.0
|
CE2
|
A:PHE226
|
4.6
|
15.3
|
1.0
|
CA
|
A:MET223
|
4.8
|
39.8
|
1.0
|
CG
|
A:MET223
|
4.8
|
23.7
|
1.0
|
O
|
B:CYS281
|
5.0
|
33.1
|
1.0
|
|
Mercury binding site 3 out
of 4 in 1tlf
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Mercury Binding Sites List in 1tlf
Mercury binding site 3 out
of 4 in the Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping
Mono view
Stereo pair view
|
A full contact list of Mercury with other atoms in the Hg binding
site number 3 of Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Hg999
b:51.3
occ:1.00
|
HE
|
D:ARG255
|
3.1
|
0.0
|
1.0
|
N
|
C:CYS281
|
3.5
|
16.0
|
1.0
|
CB
|
C:CYS281
|
3.6
|
38.6
|
1.0
|
SD
|
D:MET223
|
3.6
|
27.1
|
1.0
|
CA
|
C:CYS281
|
3.6
|
16.0
|
1.0
|
C
|
C:SER280
|
3.8
|
10.0
|
1.0
|
CB
|
C:SER280
|
3.8
|
22.7
|
1.0
|
CG
|
D:PHE226
|
3.8
|
6.8
|
1.0
|
CE
|
D:MET223
|
3.8
|
27.1
|
1.0
|
H
|
C:CYS281
|
3.9
|
0.0
|
1.0
|
O
|
C:SER280
|
3.9
|
22.7
|
1.0
|
CB
|
D:PHE226
|
3.9
|
6.8
|
1.0
|
NE
|
D:ARG255
|
4.0
|
29.2
|
1.0
|
CD1
|
D:PHE226
|
4.1
|
6.8
|
1.0
|
CG
|
D:ARG255
|
4.1
|
29.2
|
1.0
|
CD2
|
D:PHE226
|
4.3
|
6.8
|
1.0
|
CD
|
D:ARG255
|
4.4
|
29.2
|
1.0
|
OG
|
C:SER280
|
4.5
|
22.7
|
1.0
|
CA
|
C:SER280
|
4.5
|
10.0
|
1.0
|
HH21
|
D:ARG255
|
4.5
|
0.0
|
1.0
|
CE1
|
D:PHE226
|
4.7
|
6.8
|
1.0
|
CA
|
D:MET223
|
4.8
|
2.0
|
1.0
|
CE2
|
D:PHE226
|
4.9
|
6.8
|
1.0
|
O
|
D:ALA222
|
4.9
|
9.8
|
1.0
|
|
Mercury binding site 4 out
of 4 in 1tlf
Go back to
Mercury Binding Sites List in 1tlf
Mercury binding site 4 out
of 4 in the Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping
Mono view
Stereo pair view
|
A full contact list of Mercury with other atoms in the Hg binding
site number 4 of Unprecedented Quaternary Structure of E. Coli Lac Repressor Core Tetramer: Implications For Dna Looping within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Hg999
b:48.1
occ:1.00
|
SG
|
D:CYS281
|
2.3
|
25.4
|
1.0
|
H
|
D:CYS281
|
2.9
|
0.0
|
1.0
|
N
|
D:CYS281
|
3.1
|
2.0
|
1.0
|
HH11
|
C:ARG255
|
3.2
|
0.0
|
1.0
|
CA
|
D:CYS281
|
3.3
|
2.0
|
1.0
|
CB
|
D:CYS281
|
3.4
|
25.4
|
1.0
|
NH1
|
C:ARG255
|
3.6
|
32.9
|
1.0
|
HH12
|
C:ARG255
|
3.7
|
0.0
|
1.0
|
SD
|
C:MET223
|
3.7
|
27.1
|
1.0
|
OG
|
D:SER280
|
3.9
|
22.9
|
1.0
|
CD2
|
C:PHE226
|
4.0
|
13.5
|
1.0
|
CG
|
C:PHE226
|
4.0
|
13.5
|
1.0
|
CG
|
C:ARG255
|
4.0
|
32.9
|
1.0
|
C
|
D:SER280
|
4.0
|
7.5
|
1.0
|
CB
|
D:SER280
|
4.1
|
22.9
|
1.0
|
CB
|
C:PHE226
|
4.2
|
13.5
|
1.0
|
CE2
|
C:PHE226
|
4.5
|
13.5
|
1.0
|
CD1
|
C:PHE226
|
4.5
|
13.5
|
1.0
|
CZ
|
C:ARG255
|
4.6
|
32.9
|
1.0
|
CA
|
D:SER280
|
4.7
|
7.5
|
1.0
|
O
|
D:SER280
|
4.7
|
22.9
|
1.0
|
C
|
D:CYS281
|
4.8
|
2.0
|
1.0
|
HG
|
D:SER280
|
4.8
|
30.0
|
1.0
|
CA
|
C:MET223
|
4.8
|
26.6
|
1.0
|
CD
|
C:ARG255
|
4.9
|
32.9
|
1.0
|
CB
|
C:ARG255
|
4.9
|
32.9
|
1.0
|
CZ
|
C:PHE226
|
5.0
|
13.5
|
1.0
|
CE1
|
C:PHE226
|
5.0
|
13.5
|
1.0
|
|
Reference:
A.M.Friedman,
T.O.Fischmann,
T.A.Steitz.
Crystal Structure of Lac Repressor Core Tetramer and Its Implications For Dna Looping. Science V. 268 1721 1995.
ISSN: ISSN 0036-8075
PubMed: 7792597
Page generated: Sun Aug 11 01:39:34 2024
|