Mercury in PDB 1yu1: Major Tropism Determinant P3C Variant

The structure of Major Tropism Determinant P3C Variant, PDB code: 1yu1 was solved by S.A.Mcmahon, J.L.Miller, J.A.Lawton, P.Ghosh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.99 / 2.07
Space group	P 63 2 2
Cell size a, b, c (Å), α, β, γ (°)	66.545, 66.545, 334.953, 90.00, 90.00, 120.00
R / Rfree (%)	18.2 / 22.1

The structure of Major Tropism Determinant P3C Variant also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Mercury atom in the Major Tropism Determinant P3C Variant (pdb code 1yu1). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 2 binding sites of Mercury where determined in the Major Tropism Determinant P3C Variant, PDB code: 1yu1:
Jump to Mercury binding site number: 1; 2;

Mercury binding site 1 out of 2 in the Major Tropism Determinant P3C Variant


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Major Tropism Determinant P3C Variant within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg384 b:72.7 occ:1.00 HG A:MMC384 0.0 72.7 1.0 SG A:CYS375 1.4 10.9 1.0 C A:MMC384 2.4 73.0 1.0 CB A:CYS375 2.9 15.7 1.0 O A:GLY249 3.1 16.2 1.0 O A:HOH730 3.2 45.5 1.0 NH1 A:ARG251 3.4 20.4 1.0 CA A:CYS375 3.5 15.8 1.0 CA A:LYS250 3.7 16.5 1.0 C A:LYS250 3.9 17.3 1.0 C A:GLY249 3.9 16.8 1.0 O A:VAL374 4.0 15.6 1.0 N A:LYS250 4.1 16.4 1.0 N A:ARG251 4.1 16.9 1.0 CG A:ARG251 4.2 18.6 1.0 O A:LYS250 4.4 17.7 1.0 N A:ASP376 4.5 18.3 1.0 CZ A:ARG251 4.5 20.1 1.0 CD A:ARG251 4.6 18.9 1.0 C A:CYS375 4.6 17.0 1.0 N A:CYS375 4.6 15.9 1.0 CB A:ARG251 4.7 17.9 1.0 C A:VAL374 4.7 15.6 1.0 O A:HOH618 4.9 36.1 1.0 CB A:LYS250 4.9 16.4 1.0 NE A:ARG251 5.0 19.5 1.0

Mercury binding site 2 out of 2 in the Major Tropism Determinant P3C Variant


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Major Tropism Determinant P3C Variant within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg382 b:72.9 occ:1.00 HG A:MMC382 0.0 72.9 1.0 C A:MMC382 2.3 72.9 1.0 SG A:CYS114 2.3 30.9 1.0 OG1 A:THR118 3.1 27.9 1.0 CB A:CYS114 3.1 28.7 1.0 CD A:ARG120 3.2 31.7 1.0 NH1 A:ARG120 3.3 34.4 1.0 CG A:ARG120 3.3 30.4 1.0 CZ A:TYR131 3.8 28.6 1.0 CE2 A:TYR131 3.8 28.5 1.0 CE1 A:TYR131 4.0 29.0 1.0 OH A:TYR131 4.1 28.4 1.0 N A:CYS114 4.1 26.9 1.0 O A:THR118 4.1 26.8 1.0 CB A:THR118 4.1 27.7 1.0 NE A:ARG120 4.1 33.2 1.0 CZ A:ARG120 4.2 34.0 1.0 C A:THR118 4.2 27.2 1.0 CD2 A:TYR131 4.2 28.9 1.0 CA A:CYS114 4.2 28.1 1.0 CB A:ARG120 4.4 29.0 1.0 N A:VAL119 4.4 26.8 1.0 CD1 A:TYR131 4.4 29.2 1.0 N A:ARG120 4.4 26.9 1.0 CG A:TYR131 4.5 29.4 1.0 CA A:VAL119 4.6 26.5 1.0 C A:VAL119 4.7 26.6 1.0 O A:TYR112 4.7 23.5 1.0 CG A:PRO128 4.7 28.4 1.0 CA A:THR118 4.7 27.6 1.0 CB A:TYR112 4.7 22.5 1.0 C A:VAL113 4.8 25.7 1.0 OD1 A:ASP116 4.9 31.9 1.0 C A:TYR112 5.0 23.3 1.0

S.A.Mcmahon, J.L.Miller, J.A.Lawton, D.E.Kerkow, A.Hodes, M.A.Marti-Renom, S.Doulatov, E.Narayanan, A.Sali, J.F.Miller, P.Ghosh. The C-Type Lectin Fold As An Evolutionary Solution For Massive Sequence Variation Nat.Struct.Mol.Biol. V. 12 886 2005.
ISSN: ISSN 1545-9993
PubMed: 16170324
DOI: 10.1038/NSMB992