Atomistry » Mercury » PDB 1yu1-2epm » 1zi5
Atomistry »
  Mercury »
    PDB 1yu1-2epm »
      1zi5 »

Mercury in PDB 1zi5: Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide

Enzymatic activity of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide

All present enzymatic activity of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide:
2.4.1.40;

Protein crystallography data

The structure of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide, PDB code: 1zi5 was solved by J.A.Letts, N.L.Rose, Y.R.Fang, C.H.Barry, S.N.Borisova, N.O.Seto, M.M.Palcic, S.V.Evans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.55
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 52.550, 149.810, 79.930, 90.00, 90.00, 90.00
R / Rfree (%) 21.1 / 22.6

Mercury Binding Sites:

The binding sites of Mercury atom in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide (pdb code 1zi5). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 6 binding sites of Mercury where determined in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide, PDB code: 1zi5:
Jump to Mercury binding site number: 1; 2; 3; 4; 5; 6;

Mercury binding site 1 out of 6 in 1zi5

Go back to Mercury Binding Sites List in 1zi5
Mercury binding site 1 out of 6 in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg401

b:26.6
occ:0.35
SG A:CYS284 2.4 26.4 1.0
CB A:CYS284 3.1 23.0 1.0
CD2 A:LEU280 3.1 20.1 1.0
CA A:LEU306 3.9 15.8 1.0
CB A:LEU306 4.0 17.5 1.0
N A:LEU306 4.0 16.1 1.0
O A:ASP302 4.1 22.4 1.0
CG A:LEU280 4.3 20.8 1.0
O A:LEU280 4.4 19.0 1.0
CD1 A:LEU306 4.4 21.3 1.0
CA A:CYS284 4.5 21.9 1.0
C A:HIS305 4.6 16.1 1.0
HG A:HG407 4.7 26.4 0.3
CB A:HIS305 4.8 19.6 1.0
CG A:LEU306 4.8 18.8 1.0
C A:LEU280 4.9 18.2 1.0
CA A:THR281 5.0 20.1 1.0
HG A:HG402 5.0 35.8 0.4
O A:HIS305 5.0 17.2 1.0

Mercury binding site 2 out of 6 in 1zi5

Go back to Mercury Binding Sites List in 1zi5
Mercury binding site 2 out of 6 in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg402

b:35.8
occ:0.40
SD A:MET288 2.9 38.7 1.0
C A:CYS284 3.7 22.2 1.0
CB A:CYS284 3.7 23.0 1.0
N A:HIS285 3.8 22.0 1.0
CG A:MET288 3.8 31.8 1.0
O A:CYS284 3.8 23.6 1.0
CA A:HIS285 3.9 24.4 1.0
CA A:CYS284 4.4 21.9 1.0
CB A:MET288 4.5 28.2 1.0
CE A:MET288 4.6 38.2 1.0
CB A:HIS285 4.7 25.9 1.0
CB A:ASP302 4.9 30.2 1.0
O A:THR281 4.9 21.6 1.0
HG A:HG401 5.0 26.6 0.3

Mercury binding site 3 out of 6 in 1zi5

Go back to Mercury Binding Sites List in 1zi5
Mercury binding site 3 out of 6 in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg403

b:25.9
occ:0.50
SG A:CYS209 2.5 30.4 1.0
O A:HOH552 2.6 26.0 1.0
O A:HOH560 2.8 43.2 1.0
O A:VAL210 3.5 16.7 1.0
CB A:CYS209 3.6 19.6 1.0
N A:VAL210 3.6 15.5 1.0
C A:CYS209 3.6 14.7 1.0
C A:VAL210 3.8 15.9 1.0
O A:CYS209 4.0 14.7 1.0
CA A:VAL210 4.0 14.8 1.0
CA A:CYS209 4.1 17.0 1.0
O A:HOH530 4.1 22.7 1.0
CE2 A:PHE270 4.3 19.3 1.0
N A:ASP211 4.6 16.8 1.0
CD1 A:PHE121 4.6 27.4 1.0
O A:GLY267 4.7 21.4 1.0
CE1 A:PHE121 4.7 28.3 1.0
O A:THR119 4.7 17.2 1.0
CZ A:PHE270 4.7 18.2 1.0
OD2 A:ASP211 4.8 22.5 1.0
O A:HOH659 5.0 55.0 1.0

Mercury binding site 4 out of 6 in 1zi5

Go back to Mercury Binding Sites List in 1zi5
Mercury binding site 4 out of 6 in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 4 of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg404

b:31.3
occ:0.60
OG1 A:THR119 2.9 21.2 1.0
SG A:CYS209 3.2 30.4 1.0
CB A:CYS209 3.3 19.6 1.0
CB A:THR119 3.9 16.1 1.0
CG2 A:THR119 3.9 18.6 1.0
CA A:CYS209 4.2 17.0 1.0
CG1 A:VAL277 4.3 15.3 1.0
N A:CYS209 4.6 15.7 1.0
CD1 A:LEU207 4.6 21.6 1.0
CB A:LEU207 4.9 18.9 1.0
CE1 A:PHE270 5.0 18.4 1.0
CZ A:PHE270 5.0 18.2 1.0
C A:VAL208 5.0 16.7 1.0

Mercury binding site 5 out of 6 in 1zi5

Go back to Mercury Binding Sites List in 1zi5
Mercury binding site 5 out of 6 in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 5 of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg405

b:24.8
occ:0.40
SG A:CYS80 2.7 41.1 1.0
O A:GLY98 2.7 23.0 1.0
CB A:CYS80 3.1 38.0 1.0
CA A:CYS80 3.2 36.1 1.0
O A:HOH649 3.7 35.5 1.0
O A:HOH656 3.7 53.5 1.0
C A:GLY98 3.8 21.0 1.0
O A:CYS80 3.9 35.3 1.0
C A:CYS80 3.9 35.5 1.0
O A:HOH619 4.1 44.0 1.0
CA A:THR99 4.3 17.9 1.0
N A:CYS80 4.4 36.0 1.0
N A:THR99 4.5 18.3 1.0
O A:HOH589 4.5 35.0 1.0
CA A:GLY98 4.8 19.5 1.0
C A:THR99 4.9 18.2 1.0
O A:THR99 5.0 19.0 1.0
N A:ARG81 5.0 34.5 1.0

Mercury binding site 6 out of 6 in 1zi5

Go back to Mercury Binding Sites List in 1zi5
Mercury binding site 6 out of 6 in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 6 of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with H Type I Trisaccharide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg407

b:26.4
occ:0.30
SG A:CYS284 2.4 26.4 1.0
O A:HOH712 2.7 36.1 1.0
CA A:CYS284 3.2 21.9 1.0
O A:HIS305 3.2 17.2 1.0
N A:CYS284 3.3 21.2 1.0
CB A:CYS284 3.4 23.0 1.0
CB A:TYR309 3.6 15.3 1.0
O A:HOH713 3.6 25.6 1.0
C A:ALA283 3.7 21.8 1.0
C A:HIS305 3.8 16.1 1.0
CB A:HIS305 3.9 19.6 1.0
O A:ALA283 4.0 22.2 1.0
CD1 A:TYR309 4.1 14.9 1.0
CB A:ALA283 4.2 19.5 1.0
CG A:TYR309 4.2 15.6 1.0
CA A:HIS305 4.3 18.1 1.0
N A:TYR309 4.4 15.5 1.0
CA A:TYR309 4.4 15.7 1.0
O A:LEU280 4.4 19.0 1.0
C A:CYS284 4.6 22.2 1.0
CA A:ALA283 4.6 20.2 1.0
N A:LEU306 4.7 16.1 1.0
HG A:HG401 4.7 26.6 0.3
CB A:ALA287 4.7 24.9 1.0
CG A:HIS305 4.8 21.3 1.0
CD2 A:HIS305 4.9 22.4 1.0

Reference:

J.A.Letts, N.L.Rose, Y.R.Fang, C.H.Barry, S.N.Borisova, N.O.Seto, M.M.Palcic, S.V.Evans. Differential Recognition of the Type I and II H Antigen Acceptors By the Human Abo(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem. V. 281 3625 2006.
ISSN: ISSN 0021-9258
PubMed: 16326711
DOI: 10.1074/JBC.M507620200
Page generated: Wed Oct 28 18:41:10 2020

Last articles

Xe in 6AYK
Xe in 6QII
Xe in 6ASM
Xe in 5NSW
Xe in 6FY9
Xe in 5O1K
Xe in 5O27
Xe in 5M69
Xe in 5KPU
Xe in 5I63
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy