Mercury in PDB 1zjp: Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease

The structure of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease, PDB code: 1zjp was solved by J.A.Letts, N.L.Rose, Y.R.Fang, C.H.Barry, S.N.Borisova, N.O.Seto, M.M.Palcic, S.V.Evans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.59
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	52.420, 150.120, 79.140, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 23.5

The structure of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease also contains other interesting chemical elements:

Manganese	(Mn)	1 atom
Chlorine	(Cl)	1 atom

The binding sites of Mercury atom in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease (pdb code 1zjp). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 6 binding sites of Mercury where determined in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease, PDB code: 1zjp:
Jump to Mercury binding site number: 1; 2; 3; 4; 5; 6;

Mercury binding site 1 out of 6 in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg401 b:33.6 occ:0.50 SG A:CYS284 2.5 30.0 1.0 O A:HOH688 2.6 38.2 1.0 CB A:CYS284 3.1 26.9 1.0 CD2 A:LEU280 3.4 23.5 1.0 O A:ASP302 3.9 24.8 1.0 CA A:LEU306 3.9 18.8 1.0 N A:LEU306 4.0 18.7 1.0 CB A:LEU306 4.0 18.4 1.0 CD1 A:LEU306 4.4 17.7 1.0 CG A:LEU280 4.6 22.0 1.0 CA A:CYS284 4.6 26.1 1.0 O A:LEU280 4.6 20.4 1.0 C A:HIS305 4.6 20.1 1.0 CB A:HIS305 4.7 23.1 1.0 C A:ASP302 4.8 25.3 1.0 HG A:HG407 4.8 31.8 0.2 CG A:LEU306 4.9 18.0 1.0 HG A:HG403 4.9 29.4 0.3 CB A:ASP302 5.0 30.5 1.0

Mercury binding site 2 out of 6 in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg402 b:27.1 occ:0.60 SG A:CYS209 2.4 25.4 1.0 O A:HOH684 2.5 30.9 1.0 OG1 A:THR119 2.9 23.1 1.0 CB A:CYS209 3.2 19.8 1.0 CL A:CL406 3.7 32.7 0.7 CB A:THR119 3.9 19.1 1.0 CG2 A:THR119 4.0 21.4 1.0 CA A:CYS209 4.2 17.8 1.0 CG1 A:VAL277 4.4 16.9 1.0 N A:CYS209 4.7 17.9 1.0 CZ A:PHE270 4.9 20.6 1.0 CE1 A:PHE270 4.9 18.2 1.0 CD1 A:LEU207 4.9 22.4 1.0

Mercury binding site 3 out of 6 in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg403 b:29.4 occ:0.30 SG A:CYS284 2.5 30.0 1.0 O A:HOH687 2.8 43.4 1.0 O A:HIS305 3.2 19.4 1.0 CA A:CYS284 3.3 26.1 1.0 N A:CYS284 3.4 23.9 1.0 CB A:CYS284 3.5 26.9 1.0 CB A:TYR309 3.6 17.4 1.0 O A:HOH686 3.7 30.2 1.0 C A:HIS305 3.8 20.1 1.0 C A:ALA283 3.8 24.8 1.0 CB A:HIS305 3.9 23.1 1.0 CD1 A:TYR309 4.0 18.3 1.0 O A:ALA283 4.1 25.0 1.0 CG A:TYR309 4.2 16.9 1.0 CB A:ALA283 4.2 23.2 1.0 CA A:HIS305 4.3 20.6 1.0 N A:TYR309 4.3 18.6 1.0 CA A:TYR309 4.3 17.8 1.0 O A:LEU280 4.6 20.4 1.0 C A:CYS284 4.7 25.8 1.0 N A:LEU306 4.7 18.7 1.0 CA A:ALA283 4.7 23.5 1.0 CB A:ALA287 4.7 24.2 1.0 CG A:HIS305 4.8 24.6 1.0 HG A:HG401 4.9 33.6 0.5 CD2 A:HIS305 4.9 25.2 1.0

Mercury binding site 4 out of 6 in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 4 of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg404 b:31.4 occ:0.40 O A:HOH676 2.5 37.6 1.0 O A:GLY98 2.6 24.1 1.0 SG A:CYS80 2.7 48.3 1.0 CB A:CYS80 2.8 43.4 1.0 CA A:CYS80 2.9 41.0 1.0 C A:GLY98 3.8 21.9 1.0 C A:CYS80 3.8 39.5 1.0 O A:CYS80 3.9 40.1 1.0 O A:HOH609 4.0 46.0 1.0 N A:CYS80 4.1 40.5 1.0 CA A:THR99 4.3 19.9 1.0 N A:THR99 4.5 19.5 1.0 O A:HOH584 4.7 43.0 1.0 CA A:GLY98 4.8 20.3 1.0 N A:ARG81 4.8 37.6 1.0 C A:THR99 4.9 19.6 1.0 C A:PRO79 4.9 40.0 1.0 O A:PRO79 5.0 39.0 1.0

Mercury binding site 5 out of 6 in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 5 of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg405 b:22.4 occ:0.20 O A:HOH617 2.7 44.1 1.0 CL A:CL406 2.8 32.7 0.7 O A:VAL210 3.4 19.7 1.0 N A:VAL210 3.4 17.9 1.0 C A:CYS209 3.5 17.1 1.0 CB A:CYS209 3.6 19.8 1.0 C A:VAL210 3.7 18.9 1.0 O A:CYS209 3.8 16.6 1.0 CA A:VAL210 3.8 17.2 1.0 CA A:CYS209 4.0 17.8 1.0 O A:HOH527 4.0 25.6 1.0 CE2 A:PHE270 4.2 20.3 1.0 OD2 A:ASP211 4.4 27.8 1.0 N A:ASP211 4.5 20.5 1.0 O A:GLY267 4.5 21.0 1.0 CZ A:PHE270 4.6 20.6 1.0 O A:THR119 4.8 20.4 1.0 CD1 A:PHE121 5.0 33.0 1.0

Mercury binding site 6 out of 6 in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 6 of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with Galactose-Grease within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg407 b:31.8 occ:0.20 SD A:MET288 2.9 39.1 1.0 OD2 A:ASP302 3.2 36.6 1.0 N A:HIS285 3.7 26.1 1.0 CB A:CYS284 3.7 26.9 1.0 C A:CYS284 3.7 25.8 1.0 O A:CYS284 3.8 26.9 1.0 CA A:HIS285 3.9 27.8 1.0 CG A:MET288 3.9 31.0 1.0 CG A:ASP302 4.1 33.8 1.0 CA A:CYS284 4.4 26.1 1.0 CE A:MET288 4.5 37.2 1.0 CB A:HIS285 4.6 30.6 1.0 CB A:MET288 4.6 29.2 1.0 CB A:ASP302 4.8 30.5 1.0 HG A:HG401 4.8 33.6 0.5 O A:THR281 4.9 23.6 1.0 OD1 A:ASP302 5.0 36.3 1.0

J.A.Letts, N.L.Rose, Y.R.Fang, C.H.Barry, S.N.Borisova, N.O.Seto, M.M.Palcic, S.V.Evans. Differential Recognition of the Type I and II H Antigen Acceptors By the Human Abo(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem. V. 281 3625 2006.
ISSN: ISSN 0021-9258
PubMed: 16326711
DOI: 10.1074/JBC.M507620200