Atomistry » Mercury » PDB 1yu1-2epm » 2alx
Atomistry »
  Mercury »
    PDB 1yu1-2epm »
      2alx »

Mercury in PDB 2alx: Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22

Enzymatic activity of Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22

All present enzymatic activity of Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22:
1.17.4.1;

Protein crystallography data

The structure of Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22, PDB code: 2alx was solved by M.Sommerhalter, L.Saleh, J.M.Bollinger Jr., A.C.Rosenzweig, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.27 / 2.60
Space group P 61 2 2
Cell size a, b, c (Å), α, β, γ (°) 92.940, 92.940, 200.930, 90.00, 90.00, 120.00
R / Rfree (%) 22.7 / 27.6

Other elements in 2alx:

The structure of Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22 also contains other interesting chemical elements:

Manganese (Mn) 2 atoms

Mercury Binding Sites:

The binding sites of Mercury atom in the Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22 (pdb code 2alx). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 4 binding sites of Mercury where determined in the Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22, PDB code: 2alx:
Jump to Mercury binding site number: 1; 2; 3; 4;

Mercury binding site 1 out of 4 in 2alx

Go back to Mercury Binding Sites List in 2alx
Mercury binding site 1 out of 4 in the Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg403

b:61.3
occ:0.80
 SG A:CYS196 2.6 40.3 1.0
CB A:CYS196 2.8 47.0 1.0
CA A:CYS196 3.0 50.7 1.0
O A:CYS196 3.5 50.6 1.0
CG2 A:VAL200 3.5 38.8 1.0
CD1 A:TYR157 3.5 48.2 1.0
CE1 A:TYR157 3.5 49.1 1.0
C A:CYS196 3.6 50.6 1.0
CB A:TYR156 3.6 64.9 1.0
CG A:TYR157 3.8 51.0 1.0
CZ A:TYR157 3.8 48.3 1.0
CD2 A:TYR157 4.0 50.4 1.0
CE2 A:TYR157 4.0 47.1 1.0
N A:TYR157 4.0 53.0 1.0
C A:TYR156 4.2 58.0 1.0
CA A:TYR157 4.4 49.8 1.0
CB A:SER199 4.4 51.5 1.0
N A:CYS196 4.4 53.0 1.0
OH A:TYR157 4.5 47.0 1.0
O A:TYR156 4.5 59.0 1.0
CA A:TYR156 4.6 58.6 1.0
CB A:TYR157 4.6 52.0 1.0
N A:VAL200 4.6 56.4 1.0
CG A:TYR156 4.6 68.5 1.0
O A:ILE153 4.7 53.8 1.0
N A:LEU197 4.8 48.3 1.0
CB A:VAL200 4.8 43.1 1.0
OG A:SER199 4.9 54.4 1.0

Mercury binding site 2 out of 4 in 2alx

Go back to Mercury Binding Sites List in 2alx
Mercury binding site 2 out of 4 in the Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg404

b:61.3
occ:0.50
 CB A:CYS214 2.4 51.2 1.0
SG A:CYS214 2.5 54.9 1.0
OD1 A:ASN76 2.7 38.8 1.0
CD2 A:LEU290 3.2 76.2 1.0
O A:VAL210 3.3 52.8 1.0
CG A:ASN76 3.6 39.0 1.0
CA A:CYS214 3.9 66.0 1.0
CD1 A:LEU304 3.9 70.8 1.0
C A:VAL210 4.2 52.5 1.0
CA A:SER211 4.2 54.1 1.0
ND2 A:ASN76 4.3 35.1 1.0
CG1 A:VAL210 4.3 43.5 1.0
N A:CYS214 4.3 65.6 1.0
O A:CYS214 4.5 67.3 1.0
NE1 A:TRP286 4.5 75.5 1.0
C A:CYS214 4.5 65.7 1.0
CB A:ASN76 4.5 38.9 1.0
CD1 A:TRP286 4.6 76.3 1.0
N A:SER211 4.6 54.4 1.0
CG A:LEU290 4.7 76.6 1.0
O A:SER211 4.9 52.8 1.0
C A:SER211 5.0 52.0 1.0

Mercury binding site 3 out of 4 in 2alx

Go back to Mercury Binding Sites List in 2alx
Mercury binding site 3 out of 4 in the Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg405

b:61.3
occ:0.30
 OE2 A:GLU309 2.8 67.8 1.0
SG A:CYS305 3.1 0.4 1.0
CD A:GLU309 3.6 66.3 1.0
N A:GLN306 3.8 65.0 1.0
CA A:GLN306 3.8 62.5 1.0
C A:CYS305 3.8 52.2 1.0
O A:CYS305 3.9 53.2 1.0
CB A:CYS305 4.1 90.2 1.0
OE1 A:GLU309 4.2 66.0 1.0
CB A:GLN306 4.3 60.2 1.0
CG A:GLU309 4.5 64.2 1.0
CA A:CYS305 4.6 54.5 1.0
CG A:GLN306 4.8 61.0 1.0
NH1 A:ARG328 4.9 0.6 1.0
O A:ASP302 4.9 56.9 1.0

Mercury binding site 4 out of 4 in 2alx

Go back to Mercury Binding Sites List in 2alx
Mercury binding site 4 out of 4 in the Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 4 of Ribonucleotide Reductase R2 From Escherichia Coli in Space Group P6(1)22 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg406

b:61.3
occ:0.30
 CB A:CYS272 2.8 74.9 1.0
SG A:CYS272 2.9 75.8 1.0
CE A:MET198 3.1 74.4 1.0
OH A:TYR194 3.4 73.5 1.0
CE2 A:TYR194 3.6 71.3 1.0
O A:CYS268 3.9 0.4 1.0
CZ A:TYR194 4.0 71.8 1.0
O A:ALA265 4.2 95.5 1.0
CA A:CYS272 4.3 98.9 1.0
CD2 A:LEU321 4.6 46.0 1.0
CA A:LYS269 4.6 73.7 1.0
O A:LYS269 4.7 70.6 1.0
CD A:LYS269 4.7 0.3 1.0
CD2 A:TYR194 4.8 68.8 1.0
C A:CYS268 4.9 1.0 1.0
C A:CYS272 4.9 98.3 1.0
SD A:MET198 4.9 74.0 1.0
N A:CYS272 5.0 98.3 1.0
CD1 A:LEU321 5.0 48.0 1.0

Reference:

M.Sommerhalter, L.Saleh, J.M.Bollinger, A.C.Rosenzweig. Structure of Escherichia Coli Ribonucleotide Reductase R2 in Space Group P6122. Acta Crystallogr.,Sect.D V. 61 1649 2005.
ISSN: ISSN 0907-4449
PubMed: 16301799
DOI: 10.1107/S0907444905034062
Page generated: Sun Dec 13 19:06:21 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy