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Atomistry » Mercury » PDB 2esw-2o1f » 2fmz » |
Mercury in PDB 2fmz: Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, Va, VII and Xiv with L- and D- Phenylalanine, Structure with D- Phenylalanine.Enzymatic activity of Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, Va, VII and Xiv with L- and D- Phenylalanine, Structure with D- Phenylalanine.
All present enzymatic activity of Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, Va, VII and Xiv with L- and D- Phenylalanine, Structure with D- Phenylalanine.:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, Va, VII and Xiv with L- and D- Phenylalanine, Structure with D- Phenylalanine., PDB code: 2fmz
was solved by
C.Temperini,
A.Scozzafava,
D.Vullo,
C.T.Supuran,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2fmz:
The structure of Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, Va, VII and Xiv with L- and D- Phenylalanine, Structure with D- Phenylalanine. also contains other interesting chemical elements:
Mercury Binding Sites:
The binding sites of Mercury atom in the Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, Va, VII and Xiv with L- and D- Phenylalanine, Structure with D- Phenylalanine.
(pdb code 2fmz). This binding sites where shown within
5.0 Angstroms radius around Mercury atom.
In total only one binding site of Mercury was determined in the Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, Va, VII and Xiv with L- and D- Phenylalanine, Structure with D- Phenylalanine., PDB code: 2fmz: Mercury binding site 1 out of 1 in 2fmzGo back to Mercury Binding Sites List in 2fmz
Mercury binding site 1 out
of 1 in the Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, Va, VII and Xiv with L- and D- Phenylalanine, Structure with D- Phenylalanine.
Mono view Stereo pair view
Reference:
C.Temperini,
A.Scozzafava,
D.Vullo,
C.T.Supuran.
Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, Va, VII, and Xiv with L- and D-Phenylalanine and Crystallographic Analysis of Their Adducts with Isozyme II: Stereospecific Recognition Within the Active Site of An Enzyme and Its Consequences For the Drug Design. J.Med.Chem. V. 49 3019 2006.
Page generated: Sun Aug 11 02:33:12 2024
ISSN: ISSN 0022-2623 PubMed: 16686544 DOI: 10.1021/JM0603320 |
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