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Atomistry » Mercury » PDB 2esw-2o1f » 2hoc » |
Mercury in PDB 2hoc: Crystal Structure of the Human Carbonic Anhydrase II in Complex with the 5-(4-Amino-3-Chloro-5-Fluorophenylsulfonamido)-1,3,4-Thiadiazole- 2-Sulfonamide InhibitorEnzymatic activity of Crystal Structure of the Human Carbonic Anhydrase II in Complex with the 5-(4-Amino-3-Chloro-5-Fluorophenylsulfonamido)-1,3,4-Thiadiazole- 2-Sulfonamide Inhibitor
All present enzymatic activity of Crystal Structure of the Human Carbonic Anhydrase II in Complex with the 5-(4-Amino-3-Chloro-5-Fluorophenylsulfonamido)-1,3,4-Thiadiazole- 2-Sulfonamide Inhibitor:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of the Human Carbonic Anhydrase II in Complex with the 5-(4-Amino-3-Chloro-5-Fluorophenylsulfonamido)-1,3,4-Thiadiazole- 2-Sulfonamide Inhibitor, PDB code: 2hoc
was solved by
V.Menchise,
A.Di Fiore,
G.De Simone,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2hoc:
The structure of Crystal Structure of the Human Carbonic Anhydrase II in Complex with the 5-(4-Amino-3-Chloro-5-Fluorophenylsulfonamido)-1,3,4-Thiadiazole- 2-Sulfonamide Inhibitor also contains other interesting chemical elements:
Mercury Binding Sites:
The binding sites of Mercury atom in the Crystal Structure of the Human Carbonic Anhydrase II in Complex with the 5-(4-Amino-3-Chloro-5-Fluorophenylsulfonamido)-1,3,4-Thiadiazole- 2-Sulfonamide Inhibitor
(pdb code 2hoc). This binding sites where shown within
5.0 Angstroms radius around Mercury atom.
In total only one binding site of Mercury was determined in the Crystal Structure of the Human Carbonic Anhydrase II in Complex with the 5-(4-Amino-3-Chloro-5-Fluorophenylsulfonamido)-1,3,4-Thiadiazole- 2-Sulfonamide Inhibitor, PDB code: 2hoc: Mercury binding site 1 out of 1 in 2hocGo back to Mercury Binding Sites List in 2hoc
Mercury binding site 1 out
of 1 in the Crystal Structure of the Human Carbonic Anhydrase II in Complex with the 5-(4-Amino-3-Chloro-5-Fluorophenylsulfonamido)-1,3,4-Thiadiazole- 2-Sulfonamide Inhibitor
Mono view Stereo pair view
Reference:
V.Menchise,
G.D.Simone,
A.D.Fiore,
A.Scozzafava,
C.T.Supuran.
Carbonic Anhydrase Inhibitors: X-Ray Crystallographic Studies For the Binding of 5-Amino-1,3,4-Thiadiazole-2-Sulfonamide and 5-(4-Amino-3-Chloro-5-Fluorophenylsulfonamido)-1,3,4- Thiadiazole-2-Sulfonamide to Human Isoform II. Bioorg.Med.Chem.Lett. V. 16 6204 2006.
Page generated: Sun Dec 13 19:07:09 2020
ISSN: ISSN 0960-894X PubMed: 17000110 DOI: 10.1016/J.BMCL.2006.09.022 |
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