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Mercury in PDB 2o1g: Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T

Protein crystallography data

The structure of Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T, PDB code: 2o1g was solved by J.A.Letts, S.N.Borisova, S.V.Evans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.71
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 52.720, 150.160, 79.550, 90.00, 90.00, 90.00
R / Rfree (%) 18.3 / 21.8

Mercury Binding Sites:

The binding sites of Mercury atom in the Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T (pdb code 2o1g). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 5 binding sites of Mercury where determined in the Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T, PDB code: 2o1g:
Jump to Mercury binding site number: 1; 2; 3; 4; 5;

Mercury binding site 1 out of 5 in 2o1g

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Mercury binding site 1 out of 5 in the Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg401

b:32.8
occ:0.50
SG A:CYS284 2.5 18.4 0.5
O A:HOH507 2.5 31.6 1.0
O A:HIS305 3.1 20.0 1.0
CA A:CYS284 3.3 22.8 0.5
CA A:CYS284 3.3 25.8 0.5
N A:CYS284 3.4 25.6 0.5
N A:CYS284 3.4 22.7 0.5
CB A:CYS284 3.4 22.3 0.5
O A:HOH460 3.5 31.0 1.0
CB A:TYR309 3.6 18.8 1.0
C A:HIS305 3.8 21.1 1.0
CB A:CYS284 3.8 26.5 0.5
C A:ALA283 3.8 24.7 1.0
CB A:HIS305 3.9 23.3 1.0
O A:ALA283 4.0 26.1 1.0
CD1 A:TYR309 4.0 18.8 1.0
CG A:TYR309 4.2 14.8 1.0
CA A:TYR309 4.2 19.5 1.0
CA A:HIS305 4.3 22.3 1.0
CB A:ALA283 4.3 22.9 1.0
N A:TYR309 4.3 20.4 1.0
O A:HOH555 4.4 40.7 1.0
O A:LEU280 4.6 20.4 1.0
N A:LEU306 4.6 19.7 1.0
C A:CYS284 4.6 25.9 0.5
C A:CYS284 4.7 24.4 0.5
SG A:CYS284 4.7 30.4 0.5
CA A:ALA283 4.7 24.8 1.0
CB A:ALA287 4.8 26.5 1.0
CG A:HIS305 4.8 26.3 1.0
HG A:HG403 4.8 33.2 0.5
CD2 A:HIS305 4.9 29.5 1.0
O A:CYS284 4.9 24.6 0.5

Mercury binding site 2 out of 5 in 2o1g

Go back to Mercury Binding Sites List in 2o1g
Mercury binding site 2 out of 5 in the Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg402

b:39.7
occ:0.20
SD A:MET288 2.5 39.3 1.0
SG A:CYS284 2.7 30.4 0.5
CB A:CYS284 3.7 26.5 0.5
O A:CYS284 3.7 24.0 0.5
CE A:MET288 3.7 39.7 1.0
C A:CYS284 3.7 24.4 0.5
N A:HIS285 3.8 25.4 1.0
CB A:CYS284 3.9 22.3 0.5
C A:CYS284 3.9 25.9 0.5
CG A:MET288 3.9 30.7 1.0
CA A:HIS285 4.0 27.9 1.0
O A:CYS284 4.2 24.6 0.5
OD2 A:ASP302 4.3 41.9 1.0
CA A:CYS284 4.4 25.8 0.5
CG A:ASP302 4.4 37.9 1.0
OD1 A:ASP302 4.4 43.6 1.0
CA A:CYS284 4.5 22.8 0.5
CB A:MET288 4.6 28.6 1.0
CB A:HIS285 4.6 28.9 1.0
O A:THR281 4.8 23.4 1.0
HG A:HG403 4.9 33.2 0.5

Mercury binding site 3 out of 5 in 2o1g

Go back to Mercury Binding Sites List in 2o1g
Mercury binding site 3 out of 5 in the Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg403

b:33.2
occ:0.50
SG A:CYS284 2.4 18.4 0.5
SG A:CYS284 2.8 30.4 0.5
CB A:CYS284 3.0 22.3 0.5
CB A:CYS284 3.0 26.5 0.5
CD2 A:LEU280 3.3 23.1 1.0
N A:LEU306 3.7 19.7 1.0
CA A:LEU306 3.8 19.2 1.0
O A:ASP302 3.9 24.4 1.0
CB A:LEU306 4.0 19.2 1.0
CD1 A:LEU306 4.3 21.0 1.0
C A:HIS305 4.4 21.1 1.0
CA A:CYS284 4.4 25.8 0.5
CG A:LEU280 4.5 21.1 1.0
CA A:CYS284 4.5 22.8 0.5
O A:LEU280 4.5 20.4 1.0
O A:HOH584 4.6 49.0 1.0
CB A:HIS305 4.6 23.3 1.0
HG A:HG401 4.8 32.8 0.5
C A:ASP302 4.8 24.9 1.0
O A:HIS305 4.9 20.0 1.0
CG A:LEU306 4.9 19.1 1.0
HG A:HG402 4.9 39.7 0.2

Mercury binding site 4 out of 5 in 2o1g

Go back to Mercury Binding Sites List in 2o1g
Mercury binding site 4 out of 5 in the Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 4 of Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg404

b:30.4
occ:0.80
O A:HOH517 1.4 21.3 1.0
SG A:CYS209 2.3 25.4 1.0
O A:HOH577 2.4 26.9 1.0
OG1 A:THR119 2.8 23.2 1.0
CB A:CYS209 3.3 20.8 1.0
O A:HOH406 3.6 15.0 1.0
CB A:THR119 3.8 22.7 1.0
CG2 A:THR119 4.0 24.1 1.0
CA A:CYS209 4.1 18.9 1.0
CG1 A:VAL277 4.4 15.7 1.0
N A:CYS209 4.8 17.2 1.0
CD1 A:LEU207 4.8 25.0 1.0
CZ A:PHE270 4.9 22.3 1.0
CE1 A:PHE270 5.0 20.6 1.0

Mercury binding site 5 out of 5 in 2o1g

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Mercury binding site 5 out of 5 in the Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 5 of Natural Occurring Mutant of Human Abo(H) Galactosyltransferase: Gtb/M214T within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg405

b:30.8
occ:0.80
SG A:CYS80 2.2 33.3 1.0
O A:GLY98 2.8 25.0 1.0
CB A:CYS80 3.1 28.5 1.0
O A:HOH496 3.3 42.8 1.0
O A:HOH508 3.4 32.1 1.0
CA A:CYS80 3.4 29.4 1.0
O A:HOH504 3.7 30.5 1.0
O A:HOH464 3.7 31.5 1.0
C A:GLY98 4.0 23.0 1.0
O A:HOH583 4.0 35.7 1.0
O A:HOH425 4.0 30.4 1.0
N A:CYS80 4.2 30.1 1.0
CA A:THR99 4.3 19.1 1.0
O A:THR99 4.5 22.7 1.0
C A:THR99 4.6 19.2 1.0
C A:CYS80 4.6 29.4 1.0
N A:THR99 4.7 19.0 1.0
O A:CYS80 4.7 30.3 1.0

Reference:

M.Persson, J.A.Letts, B.Hosseini-Maaf, S.N.Borisova, M.M.Palcic, S.V.Evans, M.L.Olsson. Structural Effects of Naturally Occurring Human Blood Group B Galactosyltransferase Mutations Adjacent to the Dxd Motif. J.Biol.Chem. V. 282 9564 2007.
ISSN: ISSN 0021-9258
PubMed: 17259183
DOI: 10.1074/JBC.M610998200
Page generated: Sun Dec 13 19:07:42 2020

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