Atomistry » Mercury » PDB 2o1g-3b4f » 2tpi
Atomistry »
  Mercury »
    PDB 2o1g-3b4f »
      2tpi »

Mercury in PDB 2tpi: On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography

Enzymatic activity of On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography

All present enzymatic activity of On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography:
3.4.21.4;

Protein crystallography data

The structure of On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography, PDB code: 2tpi was solved by J.Walter, W.Steigemann, T.P.Singh, H.Bartunik, W.Bode, R.Huber, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 6.50 / 2.10
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 75.670, 84.160, 122.890, 90.00, 90.00, 90.00
R / Rfree (%) 20 / n/a

Mercury Binding Sites:

The binding sites of Mercury atom in the On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography (pdb code 2tpi). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 3 binding sites of Mercury where determined in the On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography, PDB code: 2tpi:
Jump to Mercury binding site number: 1; 2; 3;

Mercury binding site 1 out of 3 in 2tpi

Go back to Mercury Binding Sites List in 2tpi
Mercury binding site 1 out of 3 in the On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography within 5.0Å range:
probe atom residue distance (Å) B Occ
Z:Hg1

b:85.2
occ:0.33
HG Z:HG1 0.0 85.2 0.3
SG Z:CYS220 1.6 37.8 0.3
HG Z:HG1 1.8 49.2 0.3
SG Z:CYS220 2.3 60.0 0.3
SG Z:CYS191 2.3 60.0 0.3
SG Z:CYS191 2.5 37.8 0.3
O Z:HOH596 2.6 25.0 1.0
CB Z:CYS220 2.9 45.0 0.3
HG Z:HG1 3.1 83.1 0.3
CB Z:CYS220 3.2 45.0 0.3
CB Z:CYS220 3.2 27.8 0.3
CB Z:CYS191 3.4 45.0 0.3
O Z:SER146 3.5 27.0 1.0
O Z:LYS145 3.6 22.0 1.0
O Z:HOH498 3.6 23.5 1.0
SG Z:CYS220 3.6 60.0 0.3
CB Z:CYS191 3.8 27.8 0.3
CB Z:CYS191 4.0 45.0 0.3
OE1 Z:GLN192 4.0 18.4 1.0
C Z:SER146 4.1 27.0 1.0
O Z:HOH566 4.2 31.8 1.0
CA Z:CYS220 4.2 22.8 1.0
CA Z:CYS191 4.3 22.8 1.0
ND2 Z:ASN143 4.3 18.4 1.0
N Z:CYS220 4.3 22.8 1.0
O Z:HOH502 4.3 29.4 1.0
CA Z:SER146 4.3 27.0 1.0
SG Z:CYS191 4.4 60.0 0.3
O Z:CYS220 4.5 22.8 1.0
C Z:LYS145 4.6 22.0 1.0
C Z:CYS220 4.6 22.8 1.0
CB Z:ASN143 4.7 16.9 1.0
CG Z:ASN143 4.7 18.4 1.0
N Z:GLN192 4.8 17.1 1.0
CD Z:GLN192 4.9 18.4 1.0
N Z:SER146 4.9 27.0 1.0
C Z:GLY219 4.9 14.4 1.0
CG1 Z:VAL1017 5.0 15.1 1.0

Mercury binding site 2 out of 3 in 2tpi

Go back to Mercury Binding Sites List in 2tpi
Mercury binding site 2 out of 3 in the On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography within 5.0Å range:
probe atom residue distance (Å) B Occ
Z:Hg1

b:49.2
occ:0.33
HG Z:HG1 0.0 49.2 0.3
HG Z:HG1 1.7 83.1 0.3
HG Z:HG1 1.8 85.2 0.3
SG Z:CYS220 2.3 37.8 0.3
SG Z:CYS191 2.4 37.8 0.3
SG Z:CYS220 2.7 60.0 0.3
CB Z:CYS220 2.7 45.0 0.3
SG Z:CYS191 2.9 60.0 0.3
CB Z:CYS220 3.1 45.0 0.3
CB Z:CYS220 3.2 27.8 0.3
O Z:LYS145 3.2 22.0 1.0
SG Z:CYS220 3.2 60.0 0.3
CG1 Z:VAL1017 3.3 15.1 1.0
CB Z:CYS191 3.3 45.0 0.3
CA Z:SER146 3.3 27.0 1.0
CB Z:CYS191 3.5 27.8 0.3
O Z:SER146 3.5 27.0 1.0
O Z:HOH596 3.6 25.0 1.0
SG Z:CYS191 3.7 60.0 0.3
C Z:SER146 3.8 27.0 1.0
C Z:LYS145 3.8 22.0 1.0
O Z:CYS220 3.8 22.8 1.0
N Z:SER146 3.8 27.0 1.0
C Z:CYS220 3.9 22.8 1.0
CA Z:CYS220 4.0 22.8 1.0
CB Z:CYS191 4.0 45.0 0.3
CB Z:VAL1017 4.3 20.0 1.0
CA Z:CYS191 4.4 22.8 1.0
CB Z:SER146 4.5 27.0 1.0
N Z:CYS220 4.6 22.8 1.0
N Z:ALA221A 4.7 17.7 1.0
CB Z:ALA221A 4.7 17.7 1.0
OG Z:SER146 4.8 0.0 0.0
O Z:HOH566 4.8 31.8 1.0
O Z:ASN143 4.8 16.9 1.0
N Z:SER147 4.9 29.4 1.0
CA Z:LYS145 5.0 22.0 1.0
CG2 Z:VAL1017 5.0 15.1 1.0
O Z:SER190 5.0 19.5 1.0

Mercury binding site 3 out of 3 in 2tpi

Go back to Mercury Binding Sites List in 2tpi
Mercury binding site 3 out of 3 in the On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography within 5.0Å range:
probe atom residue distance (Å) B Occ
Z:Hg1

b:83.1
occ:0.33
HG Z:HG1 0.0 83.1 0.3
HG Z:HG1 1.7 49.2 0.3
CG1 Z:VAL1017 2.0 15.1 1.0
SG Z:CYS191 2.1 37.8 0.3
SG Z:CYS191 2.3 60.0 0.3
SG Z:CYS220 2.3 60.0 0.3
CB Z:CYS191 2.5 27.8 0.3
CB Z:CYS191 2.5 45.0 0.3
SG Z:CYS191 3.0 60.0 0.3
HG Z:HG1 3.1 85.2 0.3
CB Z:VAL1017 3.2 20.0 1.0
CB Z:CYS191 3.2 45.0 0.3
CB Z:CYS220 3.4 45.0 0.3
SG Z:CYS220 3.5 37.8 0.3
O Z:ASN143 3.6 16.9 1.0
CB Z:CYS220 3.7 45.0 0.3
CA Z:CYS191 3.7 22.8 1.0
CB Z:CYS220 3.7 27.8 0.3
N Z:VAL1017 3.9 20.0 1.0
O Z:LYS145 4.0 22.0 1.0
CA Z:VAL1017 4.1 20.0 1.0
N Z:CYS191 4.1 22.8 1.0
O Z:SER190 4.2 19.5 1.0
SG Z:CYS220 4.2 60.0 0.3
CG2 Z:VAL1017 4.3 15.1 1.0
C Z:LYS145 4.3 22.0 1.0
CA Z:SER146 4.3 27.0 1.0
O Z:ASP189 4.3 20.3 1.0
C Z:SER190 4.3 19.5 1.0
C Z:ASN143 4.5 16.9 1.0
N Z:SER146 4.5 27.0 1.0
C Z:CYS220 4.6 22.8 1.0
C Z:ILE1016 4.7 20.6 1.0
CA Z:CYS220 4.7 22.8 1.0
CB Z:ALA221A 4.8 17.7 1.0
N Z:LYS145 4.8 22.0 1.0
C Z:ASP189 4.8 20.3 1.0
CB Z:ASN143 4.9 16.9 1.0
O Z:CYS220 4.9 22.8 1.0
CB Z:ASP189 5.0 20.3 1.0
O Z:HOH596 5.0 25.0 1.0
C Z:THR144 5.0 20.8 1.0

Reference:

J.Walter, W.Steigemann, T.P.Singh, H.Bartunik, W.Bode, R.Huber. On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography Acta Crystallogr.,Sect.B V. 38 1462 1982.
ISSN: ISSN 0108-7681
Page generated: Sun Dec 13 19:08:20 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy