Mercury in PDB 3ckw: Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24)

All present enzymatic activity of Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24):
2.7.11.1;

The structure of Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24), PDB code: 3ckw was solved by S.S.Antonysamy, S.K.Burley, S.Buchanan, F.Chau, I.Feil, L.Wu, J.M.Sauder, New York Sgx Research Center For Structural Genomics (Nysgxrc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.58 / 1.96
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	47.430, 56.368, 61.550, 90.00, 112.69, 90.00
R / Rfree (%)	20.7 / 26.5

The binding sites of Mercury atom in the Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24) (pdb code 3ckw). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 2 binding sites of Mercury where determined in the Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24), PDB code: 3ckw:
Jump to Mercury binding site number: 1; 2;

Mercury binding site 1 out of 2 in the Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24)


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24) within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg305 b:52.7 occ:0.30 SG A:CYS62 1.5 16.8 0.7 CB A:CYS62 3.0 28.2 0.7 SG A:CYS62 3.3 32.5 0.3 O A:HOH504 3.4 50.5 1.0 CG1 A:VAL58 3.7 55.1 1.0 O A:VAL58 3.7 44.5 1.0 CD2 A:LEU120 3.8 34.8 1.0 HG A:HG306 3.9 39.4 0.1 CG1 A:VAL67 4.1 18.3 1.0 C A:VAL58 4.2 46.2 1.0 CB A:CYS62 4.3 29.8 0.3 CA A:CYS62 4.3 26.4 0.7 CA A:LEU59 4.5 46.6 1.0 N A:LEU59 4.6 47.0 1.0 N A:CYS62 4.7 38.1 0.7 CD2 A:LEU59 4.7 50.6 1.0 CB A:VAL58 4.8 49.1 1.0

Mercury binding site 2 out of 2 in the Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24)


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24) within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg306 b:39.4 occ:0.15 SG A:CYS62 1.8 32.5 0.3 SG A:CYS62 2.6 16.8 0.7 CA A:CYS62 3.0 26.4 0.7 CB A:CYS62 3.2 28.2 0.7 CB A:CYS62 3.5 29.8 0.3 N A:CYS62 3.5 38.1 0.7 O A:GLN61 3.5 40.6 0.7 CG A:LYS125 3.6 44.8 1.0 C A:GLN61 3.7 41.2 0.7 CE1 A:TYR119 3.9 36.5 1.0 HG A:HG305 3.9 52.7 0.3 CD A:LYS125 3.9 58.3 1.0 CG A:GLN61 3.9 42.4 0.3 CD2 A:LEU120 4.0 34.8 1.0 CA A:CYS62 4.1 30.9 0.3 OH A:TYR119 4.1 41.7 1.0 O A:GLN61 4.3 38.2 0.3 N A:CYS62 4.3 32.9 0.3 C A:CYS62 4.3 32.1 0.7 C A:GLN61 4.4 37.0 0.3 CZ A:TYR119 4.4 42.9 1.0 O A:VAL58 4.5 44.5 1.0 CB A:GLU123 4.6 45.3 1.0 CB A:LYS125 4.6 43.5 1.0 N A:ASP63 4.6 33.1 0.7 CD A:GLN61 4.7 42.7 0.3 CG A:GLU123 4.9 52.9 1.0 CD1 A:TYR119 4.9 36.8 1.0 CA A:GLN61 5.0 46.7 0.7

S.S.Antonysamy, S.K.Burley, S.Buchanan, F.Chau, I.Feil, L.Wu, J.M.Sauder. Crystal Structure of Sterile 20-Like Kinase 3 (MST3, STK24). To Be Published.