Mercury in PDB 3d8d: Crystal Structure of the Human FE65-PTB1 Domain

The structure of Crystal Structure of the Human FE65-PTB1 Domain, PDB code: 3d8d was solved by J.Radzimanowski, S.Ravaud, I.Sinning, K.Wild, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.00 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	43.756, 79.574, 83.974, 90.00, 90.00, 90.00
R / Rfree (%)	20.2 / 25.2

The binding sites of Mercury atom in the Crystal Structure of the Human FE65-PTB1 Domain (pdb code 3d8d). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 6 binding sites of Mercury where determined in the Crystal Structure of the Human FE65-PTB1 Domain, PDB code: 3d8d:
Jump to Mercury binding site number: 1; 2; 3; 4; 5; 6;

Mercury binding site 1 out of 6 in the Crystal Structure of the Human FE65-PTB1 Domain


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Crystal Structure of the Human FE65-PTB1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg1 b:38.3 occ:0.86 SG A:CYS369 2.3 29.4 1.0 O A:CYS369 3.1 31.8 1.0 C A:CYS369 3.3 30.6 1.0 CB A:CYS369 3.5 31.3 1.0 N A:PHE370 3.7 29.2 1.0 CA A:CYS369 4.0 30.8 1.0 N A:ALA371 4.0 29.1 1.0 CD2 A:LEU423 4.0 26.8 1.0 C A:PHE370 4.0 28.6 1.0 CA A:PHE370 4.0 28.4 1.0 O A:PHE370 4.6 27.8 1.0 CA A:ALA371 4.8 29.3 1.0 CG A:LEU423 4.8 31.4 1.0 CD1 A:LEU423 4.9 31.3 1.0 CB A:ALA371 5.0 28.7 1.0

Mercury binding site 2 out of 6 in the Crystal Structure of the Human FE65-PTB1 Domain


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Crystal Structure of the Human FE65-PTB1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg5 b:28.1 occ:0.38 SG A:CYS397 2.2 29.6 1.0 SD A:MET380 3.0 42.3 1.0 O A:ALA393 3.0 25.1 1.0 CE A:MET380 3.1 41.3 1.0 CB A:CYS397 3.2 24.4 1.0 SG A:CYS479 3.2 23.4 1.0 C A:ALA393 3.3 23.9 1.0 CB A:CYS479 3.4 24.1 1.0 CA A:VAL394 3.4 24.1 1.0 N A:VAL394 3.6 23.9 1.0 CG2 A:VAL394 4.1 25.2 1.0 CG A:MET380 4.1 35.5 1.0 CB A:ALA393 4.3 23.4 1.0 CB A:VAL394 4.3 24.5 1.0 CA A:ALA393 4.4 23.6 1.0 CA A:CYS397 4.4 24.9 1.0 C A:VAL394 4.4 24.1 1.0 N A:CYS397 4.5 24.1 1.0 O A:VAL394 4.5 24.1 1.0 CG2 A:VAL468 4.7 17.0 1.0 CA A:CYS479 4.9 24.3 1.0 CG1 A:VAL394 5.0 25.7 1.0

Mercury binding site 3 out of 6 in the Crystal Structure of the Human FE65-PTB1 Domain


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of Crystal Structure of the Human FE65-PTB1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg6 b:59.1 occ:0.49 SG A:CYS499 2.2 47.1 1.0 CB A:CYS499 2.8 47.0 1.0 CA A:CYS499 3.4 46.8 1.0 O A:CYS499 3.8 47.5 1.0 SD A:MET503 3.8 72.7 1.0 CE A:MET503 3.9 70.7 1.0 C A:CYS499 3.9 47.8 1.0 CG A:MET503 4.1 67.9 1.0 N A:CYS499 4.7 45.4 1.0 N A:SER500 4.9 49.6 1.0

Mercury binding site 4 out of 6 in the Crystal Structure of the Human FE65-PTB1 Domain


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 4 of Crystal Structure of the Human FE65-PTB1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg2 b:40.7 occ:0.89 SG B:CYS369 1.7 22.1 1.0 CB B:CYS369 3.2 30.0 1.0 O B:CYS369 3.2 29.8 1.0 C B:CYS369 3.4 29.9 1.0 N B:PHE370 3.8 29.7 1.0 CA B:CYS369 3.9 29.6 1.0 CD2 B:LEU423 3.9 28.0 1.0 C B:PHE370 4.2 30.0 1.0 N B:ALA371 4.3 30.7 1.0 CA B:PHE370 4.3 30.4 1.0 CB B:LEU423 4.6 28.9 1.0 CG B:LEU423 4.6 28.1 1.0 O B:PHE370 4.6 30.5 1.0 CD1 B:LEU423 4.6 27.2 1.0

Mercury binding site 5 out of 6 in the Crystal Structure of the Human FE65-PTB1 Domain


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 5 of Crystal Structure of the Human FE65-PTB1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg3 b:31.2 occ:0.58 SG B:CYS397 2.2 26.9 1.0 SD B:MET380 3.1 37.6 1.0 O B:ALA393 3.2 26.3 1.0 CB B:CYS397 3.2 22.6 1.0 SG B:CYS479 3.2 21.0 1.0 C B:ALA393 3.4 25.8 1.0 CB B:CYS479 3.5 20.2 1.0 N B:VAL394 3.6 25.9 1.0 CA B:VAL394 3.6 26.1 1.0 CE B:MET380 4.0 37.7 1.0 CB B:ALA393 4.1 24.8 1.0 CG B:MET380 4.3 34.1 1.0 O B:HOH555 4.3 34.6 1.0 CA B:ALA393 4.3 25.6 1.0 CA B:CYS397 4.4 23.4 1.0 C B:VAL394 4.5 25.9 1.0 N B:CYS397 4.5 23.0 1.0 O B:VAL394 4.5 25.1 1.0 CG2 B:VAL468 4.5 20.5 1.0 CG2 B:VAL394 4.6 26.1 1.0 CB B:VAL394 4.8 27.1 1.0 CA B:CYS479 5.0 21.6 1.0

Mercury binding site 6 out of 6 in the Crystal Structure of the Human FE65-PTB1 Domain


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 6 of Crystal Structure of the Human FE65-PTB1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg4 b:51.6 occ:0.61 SG B:CYS499 1.9 45.4 1.0 CB B:CYS499 2.9 45.7 1.0 CA B:CYS499 3.5 46.0 1.0 O B:CYS499 3.6 45.8 1.0 C B:CYS499 3.9 46.6 1.0 CG B:MET503 3.9 65.8 1.0 SD B:MET503 4.4 73.8 1.0 N B:CYS499 4.8 45.1 1.0 CG2 B:ILE502 5.0 56.4 1.0 N B:SER500 5.0 48.0 1.0

J.Radzimanowski, S.Ravaud, S.Schlesinger, J.Koch, K.Beyreuther, I.Sinning, K.Wild. Crystal Structure of the Human FE65-PTB1 Domain. J.Biol.Chem. V. 283 23113 2008.
ISSN: ISSN 0021-9258
PubMed: 18550529
DOI: 10.1074/JBC.M800861200