Mercury in PDB 4c7n: Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf

The structure of Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf, PDB code: 4c7n was solved by D.Wohlwend, S.Gerhardt, T.Kuekenshoener, O.Einsle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.92 / 2.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	23.701, 33.265, 61.125, 90.00, 94.65, 90.00
R / Rfree (%)	22.755 / 25.312

The binding sites of Mercury atom in the Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf (pdb code 4c7n). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 6 binding sites of Mercury where determined in the Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf, PDB code: 4c7n:
Jump to Mercury binding site number: 1; 2; 3; 4; 5; 6;

Mercury binding site 1 out of 6 in the Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg1049 b:35.6 occ:0.30 NE2 A:HIS48 1.8 70.5 1.0 CE1 A:HIS48 2.4 68.5 1.0 CD2 A:HIS48 3.0 66.8 1.0 ND1 A:HIS48 3.6 63.3 1.0 CG A:HIS48 3.9 61.7 1.0 O B:ALA48 4.4 40.9 1.0

Mercury binding site 2 out of 6 in the Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg1052 b:34.3 occ:0.40 CD2 B:HIS30 2.9 37.8 1.0 NE2 B:HIS30 3.1 42.6 1.0 HG B:HG1054 3.1 34.1 0.4 O B:HOH2020 3.2 37.9 1.0 CG B:HIS30 3.6 36.1 1.0 CE1 B:HIS30 3.8 45.6 1.0 ND1 B:HIS30 4.1 42.5 1.0 CB B:HIS30 4.5 31.5 1.0

Mercury binding site 3 out of 6 in the Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg1053 b:35.2 occ:0.42 ND1 B:HIS30 2.7 42.5 1.0 O B:HOH2020 3.0 37.9 1.0 CG B:HIS30 3.2 36.1 1.0 HG B:HG1055 3.2 38.2 0.4 CB B:HIS30 3.2 31.5 1.0 CE1 B:HIS30 3.6 45.6 1.0 O B:LYS26 4.1 27.6 1.0 O B:HOH2004 4.3 27.7 1.0 CD2 B:HIS30 4.3 37.8 1.0 NE2 B:HIS30 4.5 42.6 1.0 CA B:HIS30 4.7 26.4 1.0 C B:LYS26 4.7 30.9 1.0 CA B:LYS27 4.9 30.6 1.0

Mercury binding site 4 out of 6 in the Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 4 of Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg1054 b:34.1 occ:0.38 O B:HOH2021 3.0 44.1 1.0 HG B:HG1052 3.1 34.3 0.4 CB B:HIS34 3.3 31.5 1.0 CG B:HIS34 3.3 38.8 1.0 ND1 B:HIS34 3.4 47.7 1.0 CD2 B:HIS30 3.7 37.8 1.0 CD2 B:HIS34 4.0 42.2 1.0 CE1 B:HIS34 4.1 50.2 1.0 NE2 B:HIS30 4.2 42.6 1.0 CA B:GLU31 4.3 24.1 1.0 NE2 B:HIS34 4.4 47.8 1.0 O B:HIS30 4.5 24.2 1.0 CG B:GLU31 4.7 34.2 1.0 N B:GLU31 4.7 24.0 1.0 CA B:HIS34 4.8 25.2 1.0 C B:HIS30 4.8 25.4 1.0 O B:HOH2006 4.9 42.9 1.0 CG B:HIS30 4.9 36.1 1.0

Mercury binding site 5 out of 6 in the Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 5 of Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg1055 b:38.2 occ:0.44 O B:HOH2022 2.9 49.0 1.0 O B:HOH2003 2.9 40.7 1.0 HG B:HG1053 3.2 35.2 0.4 O B:HOH2020 4.3 37.9 1.0 CG B:LYS27 4.7 41.7 1.0 NZ B:LYS27 4.8 58.9 1.0

Mercury binding site 6 out of 6 in the Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 6 of Crystal Structure of the Synthetic Peptide IM10 in Complex with the Coiled-Coil Region of Mitf within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg1056 b:33.4 occ:0.40 OE1 B:GLU20 3.6 53.2 1.0 CD B:GLU20 4.2 53.0 1.0 OE2 B:GLU20 4.5 62.8 1.0 CB B:GLU20 5.0 40.0 1.0

T.Kukenshoner, D.Wohlwend, J.Niemoller, P.Dondapati, J.Speck, A.V.Adeniran, A.Nieth, S.Gerhardt, O.Einsle, K.M.Muller, K.M.Arndt. Improving Coiled Coil Stability While Maintaining Specificity By A Bacterial Hitchhiker Selection System. J.Struct.Biol. V. 186 335 2014.
ISSN: ISSN 1047-8477
PubMed: 24631970
DOI: 10.1016/J.JSB.2014.03.002