Atomistry » Mercury » PDB 5ca2-5l9w » 5fn7
Atomistry »
  Mercury »
    PDB 5ca2-5l9w »
      5fn7 »

Mercury in PDB 5fn7: Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2

Enzymatic activity of Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2

All present enzymatic activity of Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2:
3.1.3.48;

Protein crystallography data

The structure of Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2, PDB code: 5fn7 was solved by V.T.Chang, R.A.Fernandes, K.A.Ganzinger, S.F.Lee, C.Siebold, J.Mccoll, P.Jonsson, M.Palayret, K.Harlos, C.H.Coles, E.Y.Jones, Y.Lui, E.Huang, R.J.C.Gilbert, D.Klenerman, A.R.Aricescu, S.J.Davis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 43.00 / 2.30
Space group P 63
Cell size a, b, c (Å), α, β, γ (°) 149.610, 149.610, 52.730, 90.00, 90.00, 120.00
R / Rfree (%) 20.2 / 23.9

Mercury Binding Sites:

The binding sites of Mercury atom in the Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2 (pdb code 5fn7). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 2 binding sites of Mercury where determined in the Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2, PDB code: 5fn7:
Jump to Mercury binding site number: 1; 2;

Mercury binding site 1 out of 2 in 5fn7

Go back to Mercury Binding Sites List in 5fn7
Mercury binding site 1 out of 2 in the Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg1178

b:0.2
occ:1.00
ND1 A:HIS92 3.0 60.3 1.0
CB A:HIS92 3.6 50.2 1.0
CG A:HIS92 3.7 56.2 1.0
CA A:HIS92 3.9 48.5 1.0
CE1 A:HIS92 4.1 61.3 1.0
O A:LEU91 4.4 53.2 1.0
NE2 A:GLN90 4.5 95.0 1.0
N A:HIS92 4.6 48.4 1.0
C A:LEU91 4.8 51.8 1.0
CD2 A:HIS92 5.0 59.2 1.0

Mercury binding site 2 out of 2 in 5fn7

Go back to Mercury Binding Sites List in 5fn7
Mercury binding site 2 out of 2 in the Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Hg1179

b:0.0
occ:1.00
OE1 A:GLU112 3.1 0.4 1.0
CD A:GLU112 4.0 0.7 1.0
NZ A:LYS29 4.3 51.2 1.0
CG A:GLU112 4.6 69.3 1.0
OE2 A:GLU112 4.8 0.7 1.0

Reference:

V.T.Chang, R.A.Fernandes, K.A.Ganzinger, S.F.Lee, C.Siebold, J.Mccoll, P.Jonsson, M.Palayret, K.Harlos, C.H.Coles, E.Y.Jones, Y.Lui, E.Huang, R.J.Gilbert, D.Klenerman, A.R.Aricescu, S.J.Davis. Initiation of T Cell Signaling By CD45 Segregation at 'Close Contacts'. Nat.Immunol. V. 17 574 2016.
ISSN: ISSN 1529-2908
PubMed: 26998761
DOI: 10.1038/NI.3392
Page generated: Sun Dec 13 19:12:36 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy