Mercury in PDB 5fn7: Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2

All present enzymatic activity of Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2:
3.1.3.48;

The structure of Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2, PDB code: 5fn7 was solved by V.T.Chang, R.A.Fernandes, K.A.Ganzinger, S.F.Lee, C.Siebold, J.Mccoll, P.Jonsson, M.Palayret, K.Harlos, C.H.Coles, E.Y.Jones, Y.Lui, E.Huang, R.J.C.Gilbert, D.Klenerman, A.R.Aricescu, S.J.Davis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.00 / 2.30
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	149.610, 149.610, 52.730, 90.00, 90.00, 120.00
R / Rfree (%)	20.2 / 23.9

The binding sites of Mercury atom in the Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2 (pdb code 5fn7). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 2 binding sites of Mercury where determined in the Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2, PDB code: 5fn7:
Jump to Mercury binding site number: 1; 2;

Mercury binding site 1 out of 2 in the Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg1178 b:0.2 occ:1.00 ND1 A:HIS92 3.0 60.3 1.0 CB A:HIS92 3.6 50.2 1.0 CG A:HIS92 3.7 56.2 1.0 CA A:HIS92 3.9 48.5 1.0 CE1 A:HIS92 4.1 61.3 1.0 O A:LEU91 4.4 53.2 1.0 NE2 A:GLN90 4.5 95.0 1.0 N A:HIS92 4.6 48.4 1.0 C A:LEU91 4.8 51.8 1.0 CD2 A:HIS92 5.0 59.2 1.0

Mercury binding site 2 out of 2 in the Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Crystal Structure of Human CD45 Extracellular Region, Domains D1-D2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg1179 b:0.0 occ:1.00 OE1 A:GLU112 3.1 0.4 1.0 CD A:GLU112 4.0 0.7 1.0 NZ A:LYS29 4.3 51.2 1.0 CG A:GLU112 4.6 69.3 1.0 OE2 A:GLU112 4.8 0.7 1.0

V.T.Chang, R.A.Fernandes, K.A.Ganzinger, S.F.Lee, C.Siebold, J.Mccoll, P.Jonsson, M.Palayret, K.Harlos, C.H.Coles, E.Y.Jones, Y.Lui, E.Huang, R.J.Gilbert, D.Klenerman, A.R.Aricescu, S.J.Davis. Initiation of T Cell Signaling By CD45 Segregation at 'Close Contacts'. Nat.Immunol. V. 17 574 2016.
ISSN: ISSN 1529-2908
PubMed: 26998761
DOI: 10.1038/NI.3392