Mercury in PDB 8ctc: Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State

The structure of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State also contains other interesting chemical elements:

Sodium

(Na)

9 atoms

The binding sites of Mercury atom in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State (pdb code 8ctc). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 3 binding sites of Mercury where determined in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State, PDB code: 8ctc:
Jump to Mercury binding site number: 1; 2; 3;

Mercury binding site 1 out of 3 in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg604 b:174.8 occ:1.00 SG A:CYS269 2.1 74.5 1.0 CB A:CYS441 2.3 78.4 1.0 SG A:CYS441 2.9 85.1 1.0 CB A:CYS269 3.3 63.0 1.0 CA A:CYS441 3.6 76.4 1.0 N A:CYS441 4.1 76.3 1.0 C A:CYS441 4.1 74.0 1.0 N A:LEU442 4.2 72.4 1.0 CA A:CYS269 4.7 59.7 1.0 CG2 A:ILE270 4.7 66.8 1.0 C A:CYS269 4.7 60.6 1.0 NH1 A:ARG445 4.9 66.2 1.0 CA A:ILE266 4.9 49.8 1.0 O A:ILE266 5.0 55.7 1.0 O A:CYS441 5.0 72.2 1.0

Mercury binding site 2 out of 3 in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg604 b:174.8 occ:1.00 SG B:CYS269 2.1 74.5 1.0 CB B:CYS441 2.3 78.4 1.0 SG B:CYS441 2.9 85.1 1.0 CB B:CYS269 3.3 63.0 1.0 CA B:CYS441 3.6 76.4 1.0 N B:CYS441 4.1 76.3 1.0 C B:CYS441 4.1 74.0 1.0 N B:LEU442 4.2 72.4 1.0 CA B:CYS269 4.7 59.7 1.0 CG2 B:ILE270 4.7 66.8 1.0 C B:CYS269 4.7 60.6 1.0 NH1 B:ARG445 4.9 66.2 1.0 CA B:ILE266 4.9 49.8 1.0 O B:ILE266 5.0 55.7 1.0 O B:CYS441 5.0 72.2 1.0

Mercury binding site 3 out of 3 in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound Glutamate in An Intermediate Outward Facing State within 5.0Å range: probe atom residue distance (Å) B Occ C:Hg604 b:174.8 occ:1.00 SG C:CYS269 2.1 74.5 1.0 CB C:CYS441 2.3 78.4 1.0 SG C:CYS441 2.9 85.1 1.0 CB C:CYS269 3.3 63.0 1.0 CA C:CYS441 3.6 76.4 1.0 N C:CYS441 4.1 76.3 1.0 C C:CYS441 4.1 74.0 1.0 N C:LEU442 4.2 72.4 1.0 CA C:CYS269 4.7 59.7 1.0 CG2 C:ILE270 4.7 66.8 1.0 C C:CYS269 4.7 60.6 1.0 NH1 C:ARG445 4.9 66.2 1.0 CA C:ILE266 4.9 49.8 1.0 O C:ILE266 5.0 55.7 1.0 O C:CYS441 5.0 72.2 1.0

B.Qiu, O.Boudker. Symport and Antiport Mechanisms of Human Glutamate Transporters Nat Commun 2023.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-023-38120-5