Mercury in PDB 9d66: Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State

The structure of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State also contains other interesting chemical elements:

Sodium

(Na)

9 atoms

The binding sites of Mercury atom in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State (pdb code 9d66). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 3 binding sites of Mercury where determined in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State, PDB code: 9d66:
Jump to Mercury binding site number: 1; 2; 3;

Mercury binding site 1 out of 3 in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg604 b:196.9 occ:1.00 SG A:CYS269 2.1 69.4 1.0 CB A:CYS441 2.3 60.4 1.0 SG A:CYS441 2.8 71.8 1.0 CB A:CYS269 3.1 58.6 1.0 CA A:CYS441 3.5 52.5 1.0 N A:CYS441 3.9 51.9 1.0 C A:CYS441 4.1 52.8 1.0 N A:LEU442 4.3 54.4 1.0 O A:ALA438 4.3 60.1 1.0 CA A:CYS269 4.4 56.0 1.0 C A:CYS269 4.5 57.3 1.0 CG2 A:ILE270 4.7 57.1 1.0 O A:CYS269 4.8 62.0 1.0 N A:ILE270 4.8 56.9 1.0 O A:CYS441 4.8 53.6 1.0

Mercury binding site 2 out of 3 in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State within 5.0Å range: probe atom residue distance (Å) B Occ B:Hg604 b:196.9 occ:1.00 SG B:CYS269 2.1 69.4 1.0 CB B:CYS441 2.3 60.4 1.0 SG B:CYS441 2.8 71.8 1.0 CB B:CYS269 3.1 58.6 1.0 CA B:CYS441 3.5 52.5 1.0 N B:CYS441 3.9 51.9 1.0 C B:CYS441 4.1 52.8 1.0 N B:LEU442 4.3 54.4 1.0 O B:ALA438 4.3 60.1 1.0 CA B:CYS269 4.4 56.0 1.0 C B:CYS269 4.5 57.3 1.0 CG2 B:ILE270 4.7 57.1 1.0 O B:CYS269 4.8 62.0 1.0 O B:CYS441 4.8 53.6 1.0 N B:ILE270 4.8 56.9 1.0

Mercury binding site 3 out of 3 in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Aspartate in An Intermediate Outward Facing State within 5.0Å range: probe atom residue distance (Å) B Occ C:Hg605 b:196.9 occ:1.00 SG C:CYS269 2.1 69.4 1.0 CB C:CYS441 2.3 60.4 1.0 SG C:CYS441 2.8 71.8 1.0 CB C:CYS269 3.1 58.6 1.0 CA C:CYS441 3.5 52.5 1.0 N C:CYS441 3.9 51.9 1.0 C C:CYS441 4.1 52.8 1.0 N C:LEU442 4.3 54.4 1.0 O C:ALA438 4.3 60.1 1.0 CA C:CYS269 4.4 56.0 1.0 C C:CYS269 4.5 57.3 1.0 CG2 C:ILE270 4.7 57.1 1.0 O C:CYS269 4.8 62.0 1.0 N C:ILE270 4.8 56.9 1.0 O C:CYS441 4.8 53.6 1.0

B.Qiu, O.Boudker. Structural Basis of the Excitatory Amino Acid Transporter 3 Substrate Recognition. Biorxiv 2024.
ISSN: ISSN 2692-8205
PubMed: 39282329
DOI: 10.1101/2024.09.05.611541