Mercury in PDB 7dir: Structure of PFGRX1 with Mercury

All present enzymatic activity of Structure of PFGRX1 with Mercury:
1.8.4.2;

The structure of Structure of PFGRX1 with Mercury, PDB code: 7dir was solved by Y.Manickam, A.Sharma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.08 / 1.65
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	48.16, 48.16, 82.463, 90, 90, 120
R / Rfree (%)	15.3 / 18.5

The binding sites of Mercury atom in the Structure of PFGRX1 with Mercury (pdb code 7dir). This binding sites where shown within 5.0 Angstroms radius around Mercury atom.
In total 3 binding sites of Mercury where determined in the Structure of PFGRX1 with Mercury, PDB code: 7dir:
Jump to Mercury binding site number: 1; 2; 3;

Mercury binding site 1 out of 3 in the Structure of PFGRX1 with Mercury


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 1 of Structure of PFGRX1 with Mercury within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg203 b:28.3 occ:0.67 O A:HOH395 2.4 28.8 1.0 OD1 A:ASP89 2.6 21.3 1.0 SG A:CYS88 2.6 23.6 1.0 CB A:CYS88 3.4 18.4 1.0 C A:CYS88 3.5 22.1 1.0 CD1 A:TYR31 3.5 20.9 1.0 N A:ASP89 3.6 18.0 1.0 O A:CYS88 3.6 19.5 1.0 CG2 A:VAL92 3.7 22.2 1.0 CE1 A:TYR31 3.8 20.8 1.0 CA A:ASP89 3.8 18.6 1.0 CG A:ASP89 3.8 19.4 1.0 CD A:LYS34 3.9 22.8 1.0 CE A:LYS34 4.0 26.2 1.0 CA A:CYS88 4.1 19.4 1.0 CB A:ASP89 4.4 19.1 1.0 CB A:VAL92 4.5 20.6 1.0 CG A:TYR31 4.6 21.0 1.0 OD2 A:ASP89 4.8 21.9 1.0 C3 A:MPO201 5.0 20.2 1.0

Mercury binding site 2 out of 3 in the Structure of PFGRX1 with Mercury


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 2 of Structure of PFGRX1 with Mercury within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg204 b:44.4 occ:0.19 O A:HOH327 2.2 36.7 0.8 ND1 A:HIS49 2.4 33.3 1.0 CG A:HIS49 3.1 27.4 1.0 CE1 A:HIS49 3.3 34.1 1.0 OD1 A:ASN19 3.3 21.5 1.0 O A:HOH394 3.3 31.1 0.4 CB A:HIS49 3.4 24.6 1.0 O A:HOH369 3.5 38.9 1.0 O A:HOH394 4.0 27.0 0.6 CG A:ASN19 4.0 24.7 1.0 ND2 A:ASN19 4.0 22.8 1.0 CD2 A:HIS49 4.1 27.1 1.0 NE2 A:HIS49 4.2 28.2 1.0 CA A:HIS49 4.4 20.1 1.0

Mercury binding site 3 out of 3 in the Structure of PFGRX1 with Mercury


Mono view


Stereo pair view

A full contact list of Mercury with other atoms in the Hg binding site number 3 of Structure of PFGRX1 with Mercury within 5.0Å range: probe atom residue distance (Å) B Occ A:Hg205 b:57.0 occ:0.22 OE1 A:GLU54 2.6 30.1 1.0 O A:THR27 3.0 28.0 1.0 OE2 A:GLU54 3.1 36.7 1.0 CD A:GLU54 3.2 33.3 1.0 CD A:LYS26 3.8 31.1 1.0 C A:THR27 4.0 24.1 1.0 CE A:LYS26 4.0 43.1 1.0 CG A:LYS26 4.2 26.9 1.0 CB A:THR27 4.3 27.9 1.0 N A:THR27 4.3 24.5 1.0 CA A:THR27 4.4 26.6 1.0 NZ A:LYS26 4.6 49.6 1.0 CG A:GLU54 4.7 23.7 1.0 CB A:LYS26 4.8 24.2 1.0 O A:GLU28 4.8 35.1 1.0

Y.Manickam, A.Sharma. Interaction of Metals with PFGRX1 To Be Published.